The genomics of Cannabis and its close relatives

• Verfasst von: Kovalchuk, Igor [VerfasserIn]
• Verfasst von: Rigault, Philippe [VerfasserIn]
• Titel: The genomics of Cannabis and its close relatives
• Verf.angabe: I. Kovalchuk, M. Pellino, P. Rigault, R. van Velzen, J. Ebersbach, J.R. Ashnest, M. Mau, M.E. Schranz, J. Alcorn, R.B. Laprairie, J.K. McKay, C. Burbridge, D. Schneider, D. Vergara, N.C. Kane, and T.F. Sharbel
• E-Jahr: 2020
• Jahr: March 10, 2020
• Umfang: 27 S.
• Fussnoten: Gesehen am 06.05.2022
• Titel Quelle: Enthalten in: Annual review of plant biology
• Ort Quelle: Palo Alto, Calif. : Annual Reviews Inc., 2002
• Jahr Quelle: 2020
• Band/Heft Quelle: 71(2020), Seite 713-739
• ISSN Quelle: 1545-2123
• DOI: doi:10.1146/annurev-arplant-081519-040203
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1750554224

Abstract

Cannabis sativa L. is an important yet controversial plant with a long history of recreational, medicinal, industrial, and agricultural use, and together with its sister genus Humulus, it represents a group of plants with a myriad of academic, agricultural, pharmaceutical, industrial, and social interests. We have performed a meta-analysis of pooled published genomics data, andwe present a comprehensive literature review on the evolutionary history of Cannabis and Humulus, including medicinal and industrial applications. We demonstrate that current Cannabis genome assemblies are incomplete, with ∼10% missing, 10-25% unmapped, and 45S and 5S ribosomal DNA clusters as well as centromeres/satellite sequences not represented. These assemblies are also ordered at a low resolution, and their consensus quality clouds the accurate annotation of complete, partial, and pseudogenized gene copies. Considering the importance of genomics in the development of any crop, this analysis underlines the need for a coordinated effort to quantify the genetic and biochemical diversity of this species.