| Online-Ressource |
Verfasst von: | Grond-Ginsbach, Caspar [VerfasserIn]  |
| Giossi, A. [VerfasserIn]  |
| Aksay, Suna Su [VerfasserIn]  |
| Engelter, S. T. [VerfasserIn]  |
| Lyrer, P. A. [VerfasserIn]  |
| Metso, T. M. [VerfasserIn]  |
| Metso, A. J. [VerfasserIn]  |
| Tatlisumak, T. [VerfasserIn]  |
| Debette, S. [VerfasserIn]  |
| Leys, D. [VerfasserIn]  |
| Thijs, V. [VerfasserIn]  |
| Bersano, A. [VerfasserIn]  |
| Abboud, S. [VerfasserIn]  |
| Kloss, Manja [VerfasserIn]  |
| Lichy, Christoph [VerfasserIn]  |
| Grau, Armin J. [VerfasserIn]  |
| Pezzini, Alessandro [VerfasserIn]  |
| Touzé, E. [VerfasserIn]  |
Titel: | Elevated peripheral leukocyte counts in acute cervical artery dissection |
Verf.angabe: | C. Grond‐Ginsbach, A. Giossi, S.S. Aksay, S.T. Engelter, P.A. Lyrer, T.M. Metso, A.J. Metso, T. Tatlisumak, S. Debette, D. Leys, V. Thijs, A. Bersano, S. Abboud, M. Kloss, C. Lichy, A. Grau, A. Pezzini and E. Touzé for the CADISP group |
E-Jahr: | 2013 |
Jahr: | 12 June 2013 |
Umfang: | 6 S. |
Teil: | volume:20 |
| year:2013 |
| number:10 |
| pages:1405-1410 |
| extent:6 |
Fussnoten: | Gesehen am 11.03.2021 |
Titel Quelle: | Enthalten in: European journal of neurology |
Ort Quelle: | Oxford [u.a.] : Wiley-Blackwell, 1994 |
Jahr Quelle: | 2013 |
Band/Heft Quelle: | 20(2013), 10, Seite 1405-1410 |
ISSN Quelle: | 1468-1331 |
Abstract: | Background and purpose It has been suggested that inflammation may play a role in the development of cervical artery dissection (CeAD), but evidence remains scarce. Methods A total of 172 patients were included with acute (< 24 h) CeAD and 348 patients with acute ischaemic stroke (IS) of other (non-CeAD) causes from the Cervical Artery Dissection and Ischemic Stroke Patients (CADISP) study, and 223 age- and sex-matched healthy control subjects. White blood cell (WBC) counts collected at admission were compared across the three groups. Results Compared with healthy control subjects, CeAD patients and non-CeAD stroke patients had higher WBC counts (P < 0.001). Patients with CeAD had higher WBC counts and were more likely to have WBC > 10 000/μl than non-CeAD stroke patients (38.4% vs. 23.0%, P < 0.001) and healthy controls (38.4% vs. 8.5%, P < 0.001). WBC counts were higher in CeAD (9.4 ± 3.3) than in IS of other causes (large artery atherosclerosis, 8.7 ± 2.3; cardioembolism, 8.2 ± 2.8; small vessel disease, 8.4 ± 2.4; undetermined cause, 8.8 ± 3.1; P = 0.022). After adjustment for age, sex, stroke severity and vascular risk factors in a multiple regression model, elevated WBC count remained associated with CeAD, as compared with non-CeAD stroke patients [odds ratio (OR) = 2.56; 95% CI 1.60-4.11; P < 0.001) and healthy controls (OR = 6.27; 95% CI 3.39-11.61; P < 0.001). Conclusions Acute CeAD was associated with particularly high WBC counts. Leukocytosis may reflect a pre-existing inflammatory state, supporting the link between inflammation and CeAD. |
DOI: | doi:10.1111/ene.12201 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: https://doi.org/https://doi.org/10.1111/ene.12201 |
| Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1111/ene.12201 |
| DOI: https://doi.org/10.1111/ene.12201 |
Datenträger: | Online-Ressource |
Sprache: | eng |
Sach-SW: | cervical artery dissection |
| inflammation |
| leukocytosis |
| white blood cell count |
K10plus-PPN: | 1751087344 |
Verknüpfungen: | → Zeitschrift |
Elevated peripheral leukocyte counts in acute cervical artery dissection / Grond-Ginsbach, Caspar [VerfasserIn]; 12 June 2013 (Online-Ressource)