Status: Bibliographieeintrag
Standort: ---
Exemplare:
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| Online-Ressource |
Verfasst von: | Hennerici, Michael G. [VerfasserIn]  |
| Bots, Michiel L. [VerfasserIn]  |
| Ford, Ian [VerfasserIn]  |
| Laurent, Stéphane [VerfasserIn]  |
| Touboul, Pierre Jean [VerfasserIn]  |
Titel: | Rationale, design and population baseline characteristics of the PERFORM Vascular Project |
Titelzusatz: | an ancillary study of the Prevention of cerebrovascular and cardiovascular Events of ischemic origin with teRutroban in patients with a history oF ischemic strOke or tRansient ischeMic attack (PERFORM) trial |
Verf.angabe: | Michael G. Hennerici, Michiel L. Bots, Ian Ford, Stéphane Laurent, Pierre Jean Touboul |
E-Jahr: | 2010 |
Jahr: | 20 May 2010 |
Umfang: | 6 S. |
Illustrationen: | Illustrationen |
Fussnoten: | Gesehen am 12.03.2021 |
Titel Quelle: | Enthalten in: Cardiovascular drugs and therapy |
Ort Quelle: | Dordrecht [u.a.] : Springer Science + Business Media B.V, 1987 |
Jahr Quelle: | 2010 |
Band/Heft Quelle: | 24(2010), 2, Seite 175-180 |
ISSN Quelle: | 1573-7241 |
Abstract: | Purpose - PERFORM is exploring the efficacy of terutroban versus aspirin for secondary prevention in patients with a history of ischemic stroke or transient ischemic attacks (TIAs). The PERFORM Vascular Project will evaluate the effect of terutroban on progression of atherosclerosis, as assessed by change in carotid intima-media thickness (CIMT) in a subgroup of patients. - - Methods and results - The Vascular Project includes structural (CIMT, carotid plaques) and functional (carotid stiffness) vascular studies in all patients showing at least one carotid plaque at entry. Expected mean follow-up is 36 months. Primary endpoint is rate of change of CIMT. Secondary endpoints include emergent plaques and assessment of carotid stiffness. 1,100 patients are required for 90% statistical power to detect treatment-related CIMT difference of 0.025 mm. The first patient was randomized in April 2006. - - Conclusions - The PERFORM Vascular Project will investigate terutroban’s effect on vascular structure and function in patients with a history of ischemic stroke or TIAs. |
DOI: | doi:10.1007/s10557-010-6231-2 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1007/s10557-010-6231-2 |
| Volltext: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887499/ |
| DOI: https://doi.org/10.1007/s10557-010-6231-2 |
Datenträger: | Online-Ressource |
Sprache: | eng |
K10plus-PPN: | 1751234096 |
Verknüpfungen: | → Zeitschrift |
Rationale, design and population baseline characteristics of the PERFORM Vascular Project / Hennerici, Michael G. [VerfasserIn]; 20 May 2010 (Online-Ressource)
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