| |  Online-Ressource |
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| Verfasst von: | Hörner-Rieber, Juliane [VerfasserIn]  |
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| | Klüter, Sebastian [VerfasserIn] |
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| | Debus, Jürgen [VerfasserIn] |
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| | Adema, Gosse [VerfasserIn] |
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| | Ansems, Marleen [VerfasserIn] |
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| | Verheij, Marcel [VerfasserIn] |
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| Titel: | MR-guided radiotherapy |
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| Titelzusatz: | the perfect partner for immunotherapy? |
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| Verf.angabe: | Juliane Hörner-Rieber, Sebastian Klüter, Jürgen Debus, Gosse Adema, Marleen Ansems and Marcel Verheij |
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| E-Jahr: | 2021 |
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| Jahr: | 02 February 2021 |
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| Umfang: | 8 S. |
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| Teil: | volume:10 |
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| | year:2021 |
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| | elocationid:615697 |
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| | pages:1-8 |
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| | extent:8 |
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| Fussnoten: | Gesehen am 06.04.2021 |
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| Titel Quelle: | Enthalten in: Frontiers in oncology |
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| Ort Quelle: | Lausanne : Frontiers Media, 2011 |
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| Jahr Quelle: | 2021 |
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| Band/Heft Quelle: | 10(2021), Artikel-ID 615697, Seite 1-8 |
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| ISSN Quelle: | 2234-943X |
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| Abstract: | During the last years, preclinical and clinical studies have emerged supporting the rationale to integrate radiotherapy and immunotherapy. Radiotherapy may enhance the effects of immunotherapy by improving tumor antigen release, antigen presentation and T-cell infiltration. Recently, magnetic resonance guided radiotherapy (MRgRT) has become clinically available. Compared to conventional radiotherapy techniques, MRgRT firstly allows for daily on-table treatment adaptation, which enables both dose escalation for increasing tumor response and superior sparing of radiosensitive organs-at-risk for reducing toxicity. The current review focuses on the potential of combining MR-guided adaptive radiotherapy with immunotherapy by providing an overview on the current status of MRgRT, latest developments in preclinical and clinical radio-immunotherapy and the unique opportunities and challenges for MR-guided radio-immunotherapy. MRgRT might especially assist in answering open questions in radio-immunotherapy regarding optimal radiation dose, fractionation, timing of immunotherapy, appropriate irradiation volumes and response prediction. |
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| DOI: | doi:10.3389/fonc.2020.615697 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: https://doi.org/10.3389/fonc.2020.615697 |
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| | Volltext: https://www.frontiersin.org/articles/10.3389/fonc.2020.615697/full |
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| | DOI: https://doi.org/10.3389/fonc.2020.615697 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Adaptive treatment |
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| | Immunotherapy |
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| | MR-guided radiotherapy (MRgRT) |
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| | preclinical |
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| | radio- immunotherapy |
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| K10plus-PPN: | 1753200970 |
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| Verknüpfungen: | → Zeitschrift |
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MR-guided radiotherapy / Hörner-Rieber, Juliane [VerfasserIn]; 02 February 2021 (Online-Ressource)
