| Online-Ressource |
Verfasst von: | Hu, Long [VerfasserIn]  |
| Dietl, Martin C. [VerfasserIn]  |
| Han, Chunyu [VerfasserIn]  |
| Rudolph, Matthias [VerfasserIn]  |
| Rominger, Frank [VerfasserIn]  |
| Hashmi, A. Stephen K. [VerfasserIn]  |
Titel: | Au-Ag bimetallic catalysis |
Titelzusatz: | 3-alkynyl benzofurans from phenols via tandem C-H alkynylation/oxy-alkynylation |
Verf.angabe: | Long Hu, Martin C. Dietl, Chunyu Han, Matthias Rudolph, Frank Rominger, and A. Stephen K. Hashmi |
E-Jahr: | 2021 |
Jahr: | 22 February 2021 |
Umfang: | 6 S. |
Fussnoten: | Gesehen am 21.04.2021 |
Titel Quelle: | Enthalten in: Angewandte Chemie. International edition |
Ort Quelle: | Weinheim : Wiley-VCH, 1998 |
Jahr Quelle: | 2021 |
Band/Heft Quelle: | 60(2021), 19 vom: Mai, Seite 10637-10642 |
ISSN Quelle: | 1521-3773 |
Abstract: | The development of new methodologies enabling a facile access to valuable heterocyclic frameworks still is an important subject of research. In this context, we describe a dual catalytic cycle merging C−H alkynylation of phenols and oxy-alkynylation of the newly introduced triple bond by using a unique redox property and the carbophilic π acidity of gold. Mechanistic studies support the participation of a bimetallic gold-silver species. The one-pot protocol offers a direct, simple, and regio-specific approach to 3-alkynyl benzofurans from readily available phenols. A broad range of substrates, including heterocycles, is transferred with excellent functional group tolerance. Thus, this methodology can be used for the late-stage incorporation of benzofurans. |
DOI: | doi:10.1002/anie.202016595 |
URL: | kostenfrei: Volltext: https://doi.org/https://doi.org/10.1002/anie.202016595 |
| kostenfrei: Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.202016595 |
| DOI: https://doi.org/10.1002/anie.202016595 |
Datenträger: | Online-Ressource |
Sprache: | eng |
Sach-SW: | Alkynylation |
| Au-Ag bimetallic catalysis |
| Benzofurans |
| Phenols |
K10plus-PPN: | 1755587570 |
Verknüpfungen: | → Zeitschrift |
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Lokale URL UB: | Zum Volltext |
Au-Ag bimetallic catalysis / Hu, Long [VerfasserIn]; 22 February 2021 (Online-Ressource)