Prostaglandins, leukotrienes, and other eicosanoids

• Titel: Prostaglandins, leukotrienes, and other eicosanoids
• Titelzusatz: from biogenesis to clinical application
• Mitwirkende: Marks, Friedrich [Hrsg.]
• Mitwirkende: Fürstenberger, Gerhard [Hrsg.]
• Verf.angabe: F. Marks, G. Fürstenberger (eds.)
• Verlagsort: Weinheim ; New York
• Verlag: Wiley-VCH
• E-Jahr: 1999
• Jahr: ©1999
• Umfang: 1 Online-Ressource (xx, 388 pages)
• Illustrationen: illustrations (some color)
• Fussnoten: Includes bibliographical references and index ; Use copy Restrictions unspecified star MiAaHDL
• ISBN: 3-527-61362-5
• ISBN: 3-527-29360-4
• ISBN: 3-527-61363-3
• ISBN: 978-3-527-29360-5
• ISBN: 978-3-527-61362-5
• ISBN: 978-3-527-61363-2
• ComputerInfo: Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
• DOI: doi:10.1002/9783527613625
• Datenträger: Online-Ressource
• Sprache: eng
• (Sekundärform): Electronic reproduction
• (Ort): [S.l.]
• (Verlag): HathiTrust Digital Library
• (E-Jahr): 2010
• Bibliogr. Hinweis: Erscheint auch als : Druck-Ausgabe: Prostaglandins, leukotrienes, and other eicosanoids. - Weinheim ; New York : Wiley-VCH, ©1999 |(DLC)00265295
• Sach-SW: Biosynthese
• Sach-SW: Eicosanoide
• Sach-SW: Pharmakodynamik
• Sach-SW: SCIENCE ; Life Sciences ; Biochemistry
• Sach-SW: Prostaglandines
• Sach-SW: Prostaglandins
• Sach-SW: Eicosanoïdes
• Sach-SW: Prostanoïdes
• Sach-SW: Leucotriènes
• Sach-SW: Eicosanoids
• Sach-SW: Leukotrienes
• Sach-SW: Prostanoids
• K10plus-PPN: 1679713523

Abstract

Arachidonic acid and companions : an abundant source of biological signals / Friedrich Marks -- The generation of free arachidonic acid / Peter Dieter -- Cyclooxygenases / Karin Müller-Decker -- Prostanoid synthases / Christian Martin and Volker Ullrich -- Lipoxygenases / Hartmut Kühn -- Oxygenation of arachidonic Acid by cytochromes P-450 / Ernst H. Oliw and Johanna Ericsson -- Renal eicosanoids / Margarete Goppelt-Strübe and Joachim Fauler -- The role of eicosanoids in reproduction / H.P. Zahradnik, B. Wetzka and W.R. Schäfer -- The role of eicosanoids in inflammation and allergy / Eva Wikström Jonsson and Sven-Erik Dahlén -- Prostanoids in the cardiovascular system / Lukasz Partyka, Arsineh Arakil Aghajanian and Helmut Sinzinger -- Eicosanoids and cancer / Friedrich Marks and Gerhard Fürstenberger -- Synthetic eicosanoids : development and clinical applications / Bernd Buchmann [and others].

Abstract

Polyunsaturated fatty acids are essential for human cell metabolism. As precursors of a very large and extremely versatile family of signaling compounds they play a key role in intracellular communication. Eicosanoids constitute one of the most abundant and prominent subfamilies of these fatty acid derivatives which are formed primarily along oxidative pathways. Prostaglandins, leukotrienes, and related eicosanoids have a modulatory function in mammalian cells and are responsible for tissue responses such as inflammation or wound repair. Increasing activity in eicosanoid research sheds new lig