Cerebral atrophy is an independent risk factor for unfavorable outcome after spontaneous supratentorial intracerebral hemorrhage

• Verfasst von: Herweh, Christian [VerfasserIn]
• Verfasst von: Prager, Eric Peter [VerfasserIn]
• Verfasst von: Sykora, Marek [VerfasserIn]
• Verfasst von: Bendszus, Martin [VerfasserIn]
• Titel: Cerebral atrophy is an independent risk factor for unfavorable outcome after spontaneous supratentorial intracerebral hemorrhage
• Verf.angabe: Herweh Christian, Prager Eric, Sykora Marek, and Bendszus Martin
• E-Jahr: 2013
• Jahr: 14 Feb 2013
• Umfang: 3 S.
• Teil: volume:44
• Teil: year:2013
• Teil: number:4
• Teil: pages:968-971
• Teil: extent:3
• Fussnoten: Gesehen am 27.04.2021
• Titel Quelle: Enthalten in: Stroke
• Ort Quelle: New York, NY : Association, 1970
• Jahr Quelle: 2013
• Band/Heft Quelle: 44(2013), 4, Seite 968-971
• ISSN Quelle: 1524-4628
• DOI: doi:10.1161/STROKEAHA.111.670901
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1756044066

Abstract

Background and Purpose—To investigate the influence of cerebral atrophy on clinical outcome in patients with supratentorial intracerebral hemorrhage.Methods—Computed tomography scans of 320 patients included in a prospective, multicenter trial were used for a segmentation analysis to determine the supratentorial cerebral volume. A logistic regression analysis was used to explore its effect on outcome after 90 days in addition to other clinical and imaging parameters.Results—Cerebral volume loss significantly reduced the odds for favorable outcome after 90 days (odds ratio=0.91; confidence interval, 0.85-0.99; P=0.02).Conclusions—Cerebral atrophy is an independent predictor of unfavorable outcome after intracerebral hemorrhage, indicating reduced functional recovery potential in these individuals.