Caught between the old and the new -Walther Straub (1874-1944), the question of drug receptors, and the rise of modern pharmacology

• Verfasst von: Prüll, Livia [VerfasserIn]
• Titel: Caught between the old and the new -Walther Straub (1874-1944), the question of drug receptors, and the rise of modern pharmacology
• Verf.angabe: Cay-Rüdiger Prüll
• Jahr: 2006
• Umfang: 25 S.
• Teil: volume:80
• Teil: year:2006
• Teil: number:3
• Teil: pages:465-489
• Teil: extent:25
• Fussnoten: Gesehen am 10.05.2021
• Titel Quelle: Enthalten in: Bulletin of the history of medicine
• Ort Quelle: Baltimore, Md. : Johns Hopkins Univ. Press, 1939
• Jahr Quelle: 2006
• Band/Heft Quelle: 80(2006), 3, Seite 465-489
• ISSN Quelle: 1086-3176
• DOI: doi:10.1353/bhm.2006.0111
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1757540431

Abstract

This paper deals with an important development of scientific pharmacology, focusing on the reaction of the German pharmacologist Walther Straub to the receptor concept, which was a new approach to explain the binding of drugs to cells in the young discipline of pharmacology after 1900. The article analyzes how Straub as an important representative of his field between 1900 and 1944 was influenced by nineteenth-century thinking, and how he developed a rival physical theory to combat the receptor concept. Straub is seen as a man of transition, who on the one side tackled a core question of drug research with modern experimental methods, but on the other side was hardly able to accept new results in chemistry.