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Verfasst von:Frietsch, Thomas [VerfasserIn]   i
 Bogdanski, Ralph [VerfasserIn]   i
 Blobner, Manfred [VerfasserIn]   i
 Werner, Christian [VerfasserIn]   i
 Kuschinsky, Wolfgang [VerfasserIn]   i
 Waschke, Klaus F. [VerfasserIn]   i
Titel:Effects of xenon on cerebral blood flow and cerebral glucose utilization in rats
Verf.angabe:Thomas Frietsch, Ralph Bogdanski, Manfred Blobner, Christian Werner, Wolfgang Kuschinsky, Klaus F. Waschke
E-Jahr:2001
Jahr:[2001]
Umfang:8 S.
Fussnoten:Gesehen am 19.05.2021
Titel Quelle:Enthalten in: Anesthesiology
Ort Quelle:Hagerstown, Md. : Lippincott Williams & Wilkins, 1940
Jahr Quelle:2001
Band/Heft Quelle:94(2001), 2, Seite 290-297
ISSN Quelle:1528-1175
Abstract:The effects of xenon inhalation on mean and local cerebral blood flow (CBF) and mean and local cerebral glucose utilization (CGU) were investigated using iodo-[14C]antipyrine and [14C]deoxyglucose autoradiography.Rats were randomly assigned to the following groups: conscious controls (n = 12); 30% (n = 12) or 70% xenon (n = 12) for 45 min for the measurement of local CBF and CGU; or 70% xenon for 2 min (n = 6) or 5 min (n = 6) for the measurement of local CBF only.Compared with conscious controls, steady state inhalation of 30 or 70% xenon did not result in changes of either local or mean CBF. However, mean CBF increased by 48 and 37% after 2 and 5 min of 70% xenon short inhalation, which was entirely caused by an increased local CBF in cortical brain regions. Mean CGU determined during steady state 30 or 70% xenon inhalation remained unchanged, although local CGU decreased in 7 (30% xenon) and 18 (70% xenon) of the 40 examined brain regions. The correlation between CBF and CGU in 40 local brain structures was maintained during steady state inhalation of both 30 and 70% xenon inhalation, although at an increased slope at 70% xenon.Effects of 70% xenon inhalation on CBF in rats are time-dependent. During steady state xenon inhalation (45 min), mean values of CBF and CGU do not differ from control values, and the relation of regional CBF to CGU is maintained, although reset at a higher level.
DOI:doi:10.1097/00000542-200102000-00019
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1097/00000542-200102000-00019
 DOI: https://doi.org/10.1097/00000542-200102000-00019
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1758163135
Verknüpfungen:→ Zeitschrift

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