Novel ultrathin poly(ethylene glycol) films as flexible platform for biological applications and plasmonics

• Verfasst von: Meyerbröker, Nikolaus [VerfasserIn]
• Verfasst von: Kriesche, Thomas [VerfasserIn]
• Verfasst von: Zharnikov, Michael [VerfasserIn]
• Titel: Novel ultrathin poly(ethylene glycol) films as flexible platform for biological applications and plasmonics
• Verf.angabe: Nikolaus Meyerbröker, Thomas Kriesche, and Michael Zharnikov
• E-Jahr: 2013
• Jahr: March 13, 2013
• Umfang: 9 S.
• Teil: volume:5
• Teil: year:2013
• Teil: number:7
• Teil: pages:2641-2649
• Teil: extent:9
• Fussnoten: Gesehen am 21.05.2021
• Titel Quelle: Enthalten in: American Chemical SocietyACS applied materials & interfaces
• Ort Quelle: Washington, DC : Soc., 2009
• Jahr Quelle: 2013
• Band/Heft Quelle: 5(2013), 7, Seite 2641-2649
• ISSN Quelle: 1944-8252
• DOI: doi:10.1021/am400065f
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 175831429X

Abstract

We present a novel approach to prepare ultrathin, biocompatible films based on cross-linking of multi-functionalized, star-branched poly(ethylene glycols) (STAR-PEGs) with tunable film thicknesses of 4-200 nm. A two-component mixture of amine- and epoxy-terminated four-arm STAR-PEGs (MN = 2000 g/mol) was spin-coated on a flat substrate. Gentle heating induced an extensive chemical cross-linking of the macromonomers, resulting in a stable, hydrogel-like film with a density close to that of bulk PEG material. The cross-linking process could be monitored in situ, exhibiting the expected kinetics. The films revealed pronounced swelling behavior, which was fully reversible and could be precisely controlled. Additionally, they provided a high affinity to citrate-stabilized gold nanoparticles (AuNP) that could be adsorbed with high densities into the PEG matrix from an aqueous solution. These novel PEG/AuNP composite films offer interesting and potentially useful optical properties. The adsorption could also be performed in a lithographic fashion, resulting in AuNP patterns imbedded into the PEG matrix.