Status: Bibliographieeintrag
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| |  Online-Ressource |
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| Verfasst von: | Yi, Buqing [VerfasserIn]  |
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| | Dalpke, Alexander [VerfasserIn] |
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| | Boutin, Sébastien [VerfasserIn] |
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| Titel: | Changes in the cystic fibrosis airway microbiome in response to CFTR modulator therapy |
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| Verf.angabe: | Buqing Yi, Alexander H. Dalpke and Sébastien Boutin |
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| E-Jahr: | 2021 |
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| Jahr: | 17 March 2021 |
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| Umfang: | 7 S. |
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| Teil: | volume:11 |
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| | year:2021 |
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| | elocationid:548613 |
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| | pages:1-7 |
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| | extent:7 |
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| Fussnoten: | Gesehen am 26.05.2021 |
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| Titel Quelle: | Enthalten in: Frontiers in Cellular and Infection Microbiology |
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| Ort Quelle: | Lausanne : Frontiers Media, 2010 |
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| Jahr Quelle: | 2021 |
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| Band/Heft Quelle: | 11(2021), Artikel-ID 548613, Seite 1-7 |
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| ISSN Quelle: | 2235-2988 |
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| Abstract: | The development of CFTR modulator therapies significantly changed the treatment scheme of people with cystic fibrosis. However, CFTR modulator therapy is still a life-long treatment, which is not able to correct the genetic defect and cure the disease. Therefore, it becomes crucial to understand the effects of such modulation of CFTR function on the airway physiology, especially on airway infections and inflammation that are currently the major life-limiting factors in people with cystic fibrosis. In this context, understanding the dynamics of airway microbiome changes in response to modulator therapy plays an essential role in developing strategies for managing airway infections. Whether and how the newly available therapies affect the airway microbiome is still at the beginning of being deciphered. We present here a brief review summarizing the latest information about microbiome alterations in light of modern cystic fibrosis modulator therapy. |
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| DOI: | doi:10.3389/fcimb.2021.548613 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: https://doi.org/10.3389/fcimb.2021.548613 |
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| | Volltext: https://www.frontiersin.org/articles/10.3389/fcimb.2021.548613/full |
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| | DOI: https://doi.org/10.3389/fcimb.2021.548613 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Airway microbiome |
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| | CFTR modulator therapy |
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| | cystic fibrosis |
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| | Host - bacteria interaction |
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| | Pseudomonas aeruginosa |
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| K10plus-PPN: | 1758989661 |
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| Verknüpfungen: | → Zeitschrift |
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Changes in the cystic fibrosis airway microbiome in response to CFTR modulator therapy / Yi, Buqing [VerfasserIn]; 17 March 2021 (Online-Ressource)
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