| Online-Ressource |
Verfasst von: | Hirsch, Daniela [VerfasserIn]  |
| Gaiser, Timo [VerfasserIn]  |
| Merx, Kirsten [VerfasserIn]  |
| Weingärtner, Simone [VerfasserIn]  |
| Forster, Michael [VerfasserIn]  |
| Hendricks, Alexander [VerfasserIn]  |
| Woenckhaus, Matthias [VerfasserIn]  |
| Schubert, Thomas [VerfasserIn]  |
| Hofheinz, Ralf-Dieter [VerfasserIn]  |
| Gencer, Deniz [VerfasserIn]  |
Titel: | Clinical responses to PD-1 inhibition and their molecular characterization in six patients with mismatch repair-deficient metastatic cancer of the digestive system |
Verf.angabe: | Daniela Hirsch, Timo Gaiser, Kirsten Merx, Simone Weingaertner, Michael Forster, Alexander Hendricks, Matthias Woenckhaus, Thomas Schubert, Ralf-Dieter Hofheinz, Deniz Gencer |
E-Jahr: | 2021 |
Jahr: | 2020 |
Umfang: | 11 S. |
Fussnoten: | Published: 09 August 2020 ; Gesehen am 02.06.2021 |
Titel Quelle: | Enthalten in: Journal of cancer research and clinical oncology |
Ort Quelle: | Berlin : Springer, 1904 |
Jahr Quelle: | 2021 |
Band/Heft Quelle: | 147(2021), 1, Seite 263-273 |
ISSN Quelle: | 1432-1335 |
Abstract: | Immune checkpoint inhibitors have shown efficacy in patients with microsatellite instability-high/mismatch repair-deficient (MSI-H/dMMR) gastrointestinal (GI) cancers. However, depth and duration of clinical response is not uniform. We assessed tumor mutation burden (TMB) as a response marker in patients with GI cancers treated with immune checkpoint inhibitors. |
DOI: | doi:10.1007/s00432-020-03335-2 |
URL: | kostenfrei: Volltext: https://doi.org/10.1007/s00432-020-03335-2 |
| DOI: https://doi.org/10.1007/s00432-020-03335-2 |
Datenträger: | Online-Ressource |
Sprache: | eng |
K10plus-PPN: | 1759433519 |
Verknüpfungen: | → Zeitschrift |
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Lokale URL UB: | Zum Volltext |
Clinical responses to PD-1 inhibition and their molecular characterization in six patients with mismatch repair-deficient metastatic cancer of the digestive system / Hirsch, Daniela [VerfasserIn]; 2020 (Online-Ressource)