| |  Online-Ressource |
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| Verfasst von: | Hirsch, Daniela [VerfasserIn]  |
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| | Gaiser, Timo [VerfasserIn] |
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| | Merx, Kirsten [VerfasserIn] |
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| | Weingärtner, Simone [VerfasserIn] |
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| | Forster, Michael [VerfasserIn] |
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| | Hendricks, Alexander [VerfasserIn] |
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| | Woenckhaus, Matthias [VerfasserIn] |
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| | Schubert, Thomas [VerfasserIn] |
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| | Hofheinz, Ralf-Dieter [VerfasserIn] |
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| | Gencer, Deniz [VerfasserIn] |
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| Titel: | Clinical responses to PD-1 inhibition and their molecular characterization in six patients with mismatch repair-deficient metastatic cancer of the digestive system |
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| Verf.angabe: | Daniela Hirsch, Timo Gaiser, Kirsten Merx, Simone Weingaertner, Michael Forster, Alexander Hendricks, Matthias Woenckhaus, Thomas Schubert, Ralf-Dieter Hofheinz, Deniz Gencer |
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| E-Jahr: | 2021 |
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| Jahr: | 2020 |
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| Umfang: | 11 S. |
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| Fussnoten: | Published: 09 August 2020 ; Gesehen am 02.06.2021 |
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| Titel Quelle: | Enthalten in: Journal of cancer research and clinical oncology |
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| Ort Quelle: | Berlin : Springer, 1904 |
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| Jahr Quelle: | 2021 |
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| Band/Heft Quelle: | 147(2021), 1, Seite 263-273 |
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| ISSN Quelle: | 1432-1335 |
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| Abstract: | Immune checkpoint inhibitors have shown efficacy in patients with microsatellite instability-high/mismatch repair-deficient (MSI-H/dMMR) gastrointestinal (GI) cancers. However, depth and duration of clinical response is not uniform. We assessed tumor mutation burden (TMB) as a response marker in patients with GI cancers treated with immune checkpoint inhibitors. |
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| DOI: | doi:10.1007/s00432-020-03335-2 |
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| URL: | kostenfrei: Volltext: https://doi.org/10.1007/s00432-020-03335-2 |
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| | DOI: https://doi.org/10.1007/s00432-020-03335-2 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| K10plus-PPN: | 1759433519 |
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| Verknüpfungen: | → Zeitschrift |
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| Lokale URL UB: |  Zum Volltext |
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Clinical responses to PD-1 inhibition and their molecular characterization in six patients with mismatch repair-deficient metastatic cancer of the digestive system / Hirsch, Daniela [VerfasserIn]; 2020 (Online-Ressource)
