| Online-Ressource |
Verfasst von: | Ziegler, Bérénice [VerfasserIn]  |
| Yiallouros, Irene [VerfasserIn]  |
| Trageser, Benjamin [VerfasserIn]  |
| Kumar, Sumit [VerfasserIn]  |
| Mercker, Moritz [VerfasserIn]  |
| Kling, Svenja [VerfasserIn]  |
| Fath, Maike [VerfasserIn]  |
| Warnken, Uwe [VerfasserIn]  |
| Schnölzer, Martina [VerfasserIn]  |
| Holstein, Thomas W. [VerfasserIn]  |
| Hartl, Markus [VerfasserIn]  |
| Marciniak-Czochra, Anna [VerfasserIn]  |
| Stetefeld, Jörg [VerfasserIn]  |
| Stöcker, Walter [VerfasserIn]  |
| Özbek, Suat [VerfasserIn]  |
Titel: | The Wnt-specific astacin proteinase HAS-7 restricts head organizer formation in Hydra |
Verf.angabe: | Berenice Ziegler, Irene Yiallouros, Benjamin Trageser, Sumit Kumar, Moritz Mercker, Svenja Kling, Maike Fath, Uwe Warnken, Martina Schnölzer, Thomas W. Holstein, Markus Hartl, Anna Marciniak-Czochra, Jörg Stetefeld, Walter Stöcker and Suat Özbek |
E-Jahr: | 2021 |
Jahr: | 09 June 2021 |
Umfang: | 22 S. |
Fussnoten: | Gesehen am 25.06.2021 |
Titel Quelle: | Enthalten in: BMC biology |
Ort Quelle: | Berlin : Springer, 2003 |
Jahr Quelle: | 2021 |
Band/Heft Quelle: | 19(2021), Artikel-ID 120, Seite 1-22 |
ISSN Quelle: | 1741-7007 |
Abstract: | The Hydra head organizer acts as a signaling center that initiates and maintains the primary body axis in steady state polyps and during budding or regeneration. Wnt/beta-Catenin signaling functions as a primary cue controlling this process, but how Wnt ligand activity is locally restricted at the protein level is poorly understood. Here we report a proteomic analysis of Hydra head tissue leading to the identification of an astacin family proteinase as a Wnt processing factor. |
DOI: | doi:10.1186/s12915-021-01046-9 |
URL: | kostenfrei: Volltext: https://doi.org/10.1186/s12915-021-01046-9 |
| kostenfrei: Volltext: https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-021-01046-9 |
| DOI: https://doi.org/10.1186/s12915-021-01046-9 |
Datenträger: | Online-Ressource |
Sprache: | eng |
Sach-SW: | Astacin |
| Axis formation |
| Hydra |
| Proteinase |
| Wnt signaling |
K10plus-PPN: | 1761250558 |
Verknüpfungen: | → Zeitschrift |
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Lokale URL UB: | Zum Volltext |
¬The¬ Wnt-specific astacin proteinase HAS-7 restricts head organizer formation in Hydra / Ziegler, Bérénice [VerfasserIn]; 09 June 2021 (Online-Ressource)