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Verfasst von:Mehls, Otto [VerfasserIn]   i
 Fine, Richard N. [VerfasserIn]   i
Titel:Growth hormone treatment after renal transplantation
Titelzusatz:a promising but underused chance to improve growth
Verf.angabe:Otto Mehls, Richard N. Fine
Jahr:2013
Umfang:4 S.
Teil:volume:28
 year:2013
 pages:1-4
 extent:4
Fussnoten:Published online: 5 September 2012 ; Gesehen am 09.07.2021
Titel Quelle:Enthalten in: Pediatric nephrology
Ort Quelle:Berlin : Springer, 1987
Jahr Quelle:2013
Band/Heft Quelle:28(2013), Seite 1-4
ISSN Quelle:1432-198X
Abstract:Growth retardation remains a clinical problem in children with chronic kidney disease (CKD) prior to and during end-stage renal disease. The growth of approximately 40 % of children on dialysis is stunted. Even so, growth hormone treatment (GH) is not used in the majority of small children prior to transplantation. Also, GH is effective in improving growth after transplantation, but again, it is only rarely used in this situation mainly for fear of triggering rejection episodes. In controlled studies, the number of patients who developed rejection episodes with GH was no greater than the number in untreated controls. However, patients with prior frequent rejection episodes developed further repeated subsequent rejection episodes. Many patients with repeated rejection episodes before GH treatment have reduced renal function and are expected to proceed to dialysis or retransplantation. We believe that in these patients, early individual decisions for or against GH treatment should be made as soon as other treatment strategies, such as steroid withdrawal, have failed or are not indicated. Decisions for GH treatment at a later pubertal age come too late for significant growth response and/or improvement of final height.
DOI:doi:10.1007/s00467-012-2293-7
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1007/s00467-012-2293-7
 DOI: https://doi.org/10.1007/s00467-012-2293-7
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1762584638
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