| Online-Ressource |
Verfasst von: | Fox, Christopher [VerfasserIn]  |
| Dreger, Peter [VerfasserIn]  |
Titel: | High-dose therapy and autologous stem cell transplantation for extra-nodal NK/T lymphoma in patients from the Western hemisphere |
Titelzusatz: | a study from the European Society for Blood and Marrow Transplantation |
Verf.angabe: | Christopher P. Fox, Ariane Boumendil, Norbert Schmitz, Herve Finel, Jian J. Luan, Gülsan Sucak, Didier Blaise, Jürgen Finke, Karl-Heinz Pflüger, Hendrik Veelken, Norbert -Claude Gorin, Xavier Poiré, Arnold Ganser, Peter Dreger, Anna Sureda |
E-Jahr: | 2015 |
Jahr: | 26 Aug 2015 |
Umfang: | 6 S. |
Teil: | volume:56 |
| year:2015 |
| number:12 |
| pages:3295-3300 |
| extent:6 |
Fussnoten: | Gesehen am 05.08.2021 |
Titel Quelle: | Enthalten in: Leukemia and lymphoma |
Ort Quelle: | London [u.a.] : Taylor & Francis Group, 1989 |
Jahr Quelle: | 2015 |
Band/Heft Quelle: | 56(2015), 12, Seite 3295-3300 |
ISSN Quelle: | 1029-2403 |
Abstract: | Extra-nodal NK/T lymphoma (ENKTL) is rare and more frequently encountered in East Asia. The role of high-dose therapy and autologous stem cell transplantation (HDT-ASCT) for ENKTL is unclear. Twenty-eight evaluable patients who had undergone HDT-ASCT in Europe from 2000-2009 were studied. The median age was 47 years and patients had received a median of two lines of prior therapy. Some 57% of patients were not in complete remission or beyond first complete remission at HDT-ASCT. The 1-year non-relapse mortality (NRM) was 11%; 2-year progression-free survival (PFS) and overall survival (OS) rates were 41% and 52%, respectively. Notably, the 2-year PFS and OS for those with stage III/IV disease were 33% and 40%, respectively, with no relapses beyond 1-year post-HDT-ASCT. This is the largest analysis of HDT-ASCT for patients with ENKTL reported from the Western hemisphere. Survival is comparable to East Asian cohorts and outcomes are encouraging for patients with advanced disease. |
DOI: | doi:10.3109/10428194.2015.1037764 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.3109/10428194.2015.1037764 |
| DOI: https://doi.org/10.3109/10428194.2015.1037764 |
Datenträger: | Online-Ressource |
Sprache: | eng |
Sach-SW: | Epstein-Barr virus |
| high-dose therapy |
| natural killer cell lymphoma |
| stem cell transplantation |
K10plus-PPN: | 176562827X |
Verknüpfungen: | → Zeitschrift |
High-dose therapy and autologous stem cell transplantation for extra-nodal NK/T lymphoma in patients from the Western hemisphere / Fox, Christopher [VerfasserIn]; 26 Aug 2015 (Online-Ressource)