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Verfasst von:Kasper, Bernd [VerfasserIn]   i
 Raut, Chandrajit P. [VerfasserIn]   i
 Gronchi, Alessandro [VerfasserIn]   i
Titel:Desmoid tumors
Titelzusatz:to treat or not to treat, that is the question
Verf.angabe:Bernd Kasper MD, Chandrajit P. Raut MD, MSc, and Alessandro Gronchi MD
E-Jahr:2020
Jahr:06 October 2020
Umfang:9 S.
Fussnoten:Gesehen am 11.08.2021
Titel Quelle:Enthalten in: Cancer
Ort Quelle:New York, NY : Wiley-Liss, 1948
Jahr Quelle:2020
Band/Heft Quelle:126(2020), 24, Seite 5213-5221
ISSN Quelle:1097-0142
Abstract:Desmoid tumors (DTs) are a rare disease of intermediate malignancy characterized histologically by a locally aggressive, monoclonal, fibroblastic proliferation and clinically by a variable and often unpredictable course. For decades, surgical resection has been the standard initial treatment approach; however, more recently, a paradigm shift toward a more conservative treatment strategy has been introduced. More than 5 years ago, The Desmoid Tumor Working Group started a consensus initiative in Europe with the aim of harmonizing the strategy among clinicians and setting up treatment recommendations for patients with DTs. This review summarizes the latest joint, global, evidence-based guideline approach to DT management. Moreover, a number of gray areas in the treatment recommendations are discussed, and possible future perspectives on the treatment armamentarium for patients with DTs are presented.
DOI:doi:10.1002/cncr.33233
URL:Volltext: https://doi.org/10.1002/cncr.33233
 Volltext: https://acsjournals.onlinelibrary.wiley.com/doi/abs/10.1002/cncr.33233
 DOI: https://doi.org/10.1002/cncr.33233
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:CTNNB1
 desmoid tumor
 European Organization for Research and Treatment of Cancer (EORTC)/Soft Tissue and Bone Sarcoma Group (STBSG)
 European Reference Network for Rare Solid Adult Cancers (EURACAN)
 medical therapy
 radiotherapy
 surgery
 The Desmoid Tumor Research Foundation (DTRF)
 β-catenin
K10plus-PPN:1766167063
Verknüpfungen:→ Zeitschrift
 
 
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