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| |  Online-Ressource |
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| Verfasst von: | Kasper, Bernd [VerfasserIn]  |
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| | Raut, Chandrajit P. [VerfasserIn] |
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| | Gronchi, Alessandro [VerfasserIn] |
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| Titel: | Desmoid tumors |
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| Titelzusatz: | to treat or not to treat, that is the question |
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| Verf.angabe: | Bernd Kasper MD, Chandrajit P. Raut MD, MSc, and Alessandro Gronchi MD |
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| E-Jahr: | 2020 |
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| Jahr: | 06 October 2020 |
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| Umfang: | 9 S. |
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| Fussnoten: | Gesehen am 11.08.2021 |
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| Titel Quelle: | Enthalten in: Cancer |
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| Ort Quelle: | New York, NY : Wiley-Liss, 1948 |
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| Jahr Quelle: | 2020 |
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| Band/Heft Quelle: | 126(2020), 24, Seite 5213-5221 |
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| ISSN Quelle: | 1097-0142 |
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| Abstract: | Desmoid tumors (DTs) are a rare disease of intermediate malignancy characterized histologically by a locally aggressive, monoclonal, fibroblastic proliferation and clinically by a variable and often unpredictable course. For decades, surgical resection has been the standard initial treatment approach; however, more recently, a paradigm shift toward a more conservative treatment strategy has been introduced. More than 5 years ago, The Desmoid Tumor Working Group started a consensus initiative in Europe with the aim of harmonizing the strategy among clinicians and setting up treatment recommendations for patients with DTs. This review summarizes the latest joint, global, evidence-based guideline approach to DT management. Moreover, a number of gray areas in the treatment recommendations are discussed, and possible future perspectives on the treatment armamentarium for patients with DTs are presented. |
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| DOI: | doi:10.1002/cncr.33233 |
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| URL: | Volltext: https://doi.org/10.1002/cncr.33233 |
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| | Volltext: https://acsjournals.onlinelibrary.wiley.com/doi/abs/10.1002/cncr.33233 |
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| | DOI: https://doi.org/10.1002/cncr.33233 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | CTNNB1 |
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| | desmoid tumor |
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| | European Organization for Research and Treatment of Cancer (EORTC)/Soft Tissue and Bone Sarcoma Group (STBSG) |
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| | European Reference Network for Rare Solid Adult Cancers (EURACAN) |
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| | medical therapy |
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| | radiotherapy |
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| | surgery |
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| | The Desmoid Tumor Research Foundation (DTRF) |
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| | β-catenin |
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| K10plus-PPN: | 1766167063 |
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| Verknüpfungen: | → Zeitschrift |
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| Lokale URL UB: |  Zum Volltext |
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Desmoid tumors / Kasper, Bernd [VerfasserIn]; 06 October 2020 (Online-Ressource)
68769881
