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| Online-Ressource |
Verfasst von: | Kasper, Bernd [VerfasserIn]  |
| Raut, Chandrajit P. [VerfasserIn]  |
| Gronchi, Alessandro [VerfasserIn]  |
Titel: | Desmoid tumors |
Titelzusatz: | to treat or not to treat, that is the question |
Verf.angabe: | Bernd Kasper MD, Chandrajit P. Raut MD, MSc, and Alessandro Gronchi MD |
E-Jahr: | 2020 |
Jahr: | 06 October 2020 |
Umfang: | 9 S. |
Fussnoten: | Gesehen am 11.08.2021 |
Titel Quelle: | Enthalten in: Cancer |
Ort Quelle: | New York, NY : Wiley-Liss, 1948 |
Jahr Quelle: | 2020 |
Band/Heft Quelle: | 126(2020), 24, Seite 5213-5221 |
ISSN Quelle: | 1097-0142 |
Abstract: | Desmoid tumors (DTs) are a rare disease of intermediate malignancy characterized histologically by a locally aggressive, monoclonal, fibroblastic proliferation and clinically by a variable and often unpredictable course. For decades, surgical resection has been the standard initial treatment approach; however, more recently, a paradigm shift toward a more conservative treatment strategy has been introduced. More than 5 years ago, The Desmoid Tumor Working Group started a consensus initiative in Europe with the aim of harmonizing the strategy among clinicians and setting up treatment recommendations for patients with DTs. This review summarizes the latest joint, global, evidence-based guideline approach to DT management. Moreover, a number of gray areas in the treatment recommendations are discussed, and possible future perspectives on the treatment armamentarium for patients with DTs are presented. |
DOI: | doi:10.1002/cncr.33233 |
URL: | Volltext: https://doi.org/10.1002/cncr.33233 |
| Volltext: https://acsjournals.onlinelibrary.wiley.com/doi/abs/10.1002/cncr.33233 |
| DOI: https://doi.org/10.1002/cncr.33233 |
Datenträger: | Online-Ressource |
Sprache: | eng |
Sach-SW: | CTNNB1 |
| desmoid tumor |
| European Organization for Research and Treatment of Cancer (EORTC)/Soft Tissue and Bone Sarcoma Group (STBSG) |
| European Reference Network for Rare Solid Adult Cancers (EURACAN) |
| medical therapy |
| radiotherapy |
| surgery |
| The Desmoid Tumor Research Foundation (DTRF) |
| β-catenin |
K10plus-PPN: | 1766167063 |
Verknüpfungen: | → Zeitschrift |
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Lokale URL UB: | Zum Volltext |
Desmoid tumors / Kasper, Bernd [VerfasserIn]; 06 October 2020 (Online-Ressource)
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