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Status: Bibliographieeintrag

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Verfasst von:Bannasch, Johannes H. [VerfasserIn]   i
 Berger, Benjamin [VerfasserIn]   i
 Schwartkop, Claus-Peter [VerfasserIn]   i
 Berning, Marco [VerfasserIn]   i
 Goetze, Oliver [VerfasserIn]   i
 Panning, Marcus [VerfasserIn]   i
 Fritz-Weltin, Miriam [VerfasserIn]   i
 Trendelenburg, George [VerfasserIn]   i
 Gelderblom, Mathias [VerfasserIn]   i
 Lütgehetmann, Marc [VerfasserIn]   i
 Stute, Fridrike [VerfasserIn]   i
 Horvatits, Thomas [VerfasserIn]   i
 Dirks, Meike [VerfasserIn]   i
 Antoni, Christoph Helmer [VerfasserIn]   i
 Behrendt, Patrick [VerfasserIn]   i
 Pischke, Sven [VerfasserIn]   i
Titel:HEV-associated neuralgic amyotrophy
Titelzusatz:a multicentric case series
Verf.angabe:Johannes H. Bannasch, Benjamin Berger, Claus-Peter Schwartkop, Marco Berning, Oliver Goetze, Marcus Panning, Miriam Fritz-Weltin, George Trendelenburg, Mathias Gelderblom, Marc Lütgehetmann, Fridrike Stute, Thomas Horvatits, Meike Dirks, Christoph Antoni, Patrick Behrendt and Sven Pischke
E-Jahr:2021
Jahr:30 May 2021
Umfang:11 S.
Fussnoten:Gesehen am 23.08.2021
Titel Quelle:Enthalten in: Pathogens
Ort Quelle:Basel : MDPI, 2012
Jahr Quelle:2021
Band/Heft Quelle:10(2021), 6, Artikel-ID 672, Seite 1-11
ISSN Quelle:2076-0817
Abstract:Background: Neuralgic amyotrophy (NA) has been described as a possible extrahepatic manifestation of hepatitis E virus (HEV) infection. Usually, HEV-associated NA occurs bilaterally. The clinical characteristics determining the course of HEV-associated NA have still not been defined. Methods: In this retrospective multicentric case series, 16 patients with HEV-associated NA were studied and compared to 176 HEV patients without NA in terms of their age, sex, and ALT levels. Results: Neither gender distribution (75% vs. 67% male) nor age (47 vs. 48 years median) differed significantly between the NA patients and controls. Eight NA patients (50%) presented with bilateral involvement—seven of these had right-side dominance and one had left-side dominance. Thirteen cases (81%) were hospitalized. Eight of these patients stayed in hospital for five to seven days, and five patients stayed for up to two weeks. The time from the onset of NA to the HEV diagnosis, as well as the diagnostic and therapeutic proceedings, showed a large variability. In total, 13 (81%) patients received treatment: 1/13 (8%) received intravenous immunoglobulins, 8/13 (62%) received glucocorticoids, 3/13 (23%) received ribavirin, and 6/13 (46%) received pregabalin/gabapentin. Patients with ages above the median (47 years) were more likely to be treated (p = 0.001). Conclusion: HEV-associated NA causes a relevant morbidity. In our case series neither the type of treatment nor the time of initiation of therapy had a significant effect on the duration of hospitalization or the course of the disease. The clinical presentation, the common diagnostic and therapeutic procedures, and the patients’ characteristics showed large variability, demonstrating the necessity of standardized protocols for this rare but relevant disease.
DOI:doi:10.3390/pathogens10060672
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.3390/pathogens10060672
 Volltext: https://www.mdpi.com/2076-0817/10/6/672
 DOI: https://doi.org/10.3390/pathogens10060672
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:Hepatitis E
 HEV
 NA
 neuralgic amyotrophy
K10plus-PPN:176766091X
Verknüpfungen:→ Zeitschrift

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