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| Verfasst von: | Becerra-Muñoz, Víctor Manuel [VerfasserIn]  |
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| | Núñez-Gil, Iván J [VerfasserIn] |
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| | Eid, Charbel Maroun [VerfasserIn] |
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| | García Aguado, Marcos [VerfasserIn] |
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| | Romero, Rodolfo [VerfasserIn] |
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| | Huang, Jia [VerfasserIn] |
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| | Mulet, Alba [VerfasserIn] |
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| | Ugo, Fabrizio [VerfasserIn] |
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| | Rametta, Francesco [VerfasserIn] |
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| | Liebetrau, Christoph [VerfasserIn] |
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| | Aparisi, Alvaro [VerfasserIn] |
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| | Fernández-Rozas, Inmaculada [VerfasserIn] |
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| | Viana-Llamas, María C [VerfasserIn] |
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| | Feltes, Gisela [VerfasserIn] |
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| | Pepe, Martino [VerfasserIn] |
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| | Moreno-Rondón, Luis A [VerfasserIn] |
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| | Cerrato, Enrico [VerfasserIn] |
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| | Raposeiras-Roubín, Sergio [VerfasserIn] |
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| | Alfonso, Emilio [VerfasserIn] |
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| | Carrero-Fernández, Ana [VerfasserIn] |
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| | Buzón-Martín, Luis [VerfasserIn] |
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| | Abumayyaleh, Mohammad S. A. [VerfasserIn] |
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| | Gonzalez, Adelina [VerfasserIn] |
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| | Fernández Ortiz, Antonio [VerfasserIn] |
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| | Macaya, Carlos [VerfasserIn] |
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| | Estrada, Vicente [VerfasserIn] |
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| | Fernández-Pérez, Cristina [VerfasserIn] |
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| | Gómez-Doblas, Juan José [VerfasserIn] |
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| Titel: | Clinical profile and predictors of in-hospital mortality among older patients hospitalised for COVID-19 |
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| Verf.angabe: | Víctor Manuel Becerra-Muñoz, Iván J. Núñez-Gil, Charbel Maroun Eid, Marcos García Aguado, Rodolfo Romero, Jia Huang, Alba Mulet, Fabrizio Ugo, Francesco Rametta, Christoph Liebetrau, Alvaro Aparisi, Inmaculada Fernández-Rozas, María C. Viana-Llamas, Gisela Feltes, Martino Pepe, Luis A. Moreno-Rondón, Enrico Cerrato, Sergio Raposeiras-Roubín, Emilio Alfonso, Ana Carrero-Fernández, Luis Buzón-Martín, Mohammad Abumayyaleh, Adelina Gonzalez, Antonio Fernández Ortiz, Carlos Macaya, Vicente Estrada, Cristina Fernández-Pérez, Juan José Gómez-Doblas |
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| Jahr: | 2021 |
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| Umfang: | 9 S. |
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| Fussnoten: | Published: 17 November 2020 ; Gesehen am 13.09.2021 |
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| Titel Quelle: | Enthalten in: Age & ageing |
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| Ort Quelle: | Oxford : Oxford Univ. Press, 1972 |
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| Jahr Quelle: | 2021 |
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| Band/Heft Quelle: | 50(2021), 2 vom: März, Seite 326-334 |
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| ISSN Quelle: | 1468-2834 |
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| Abstract: | the coronavirus disease 2019 (COVID-19) is characterized by poor outcomes and mortality, particularly in older patients.post hoc analysis of the international, multicentre, ‘real-world’ HOPE COVID-19 registry. All patients aged ≥65 years hospitalised for COVID-19 were selected. Epidemiological, clinical, analytical and outcome data were obtained. A comparative study between two age subgroups, 65-74 and ≥75 years, was performed. The primary endpoint was all cause in-hospital mortality.about, 1,520 patients aged ≥65 years (60.3% male, median age of 76 [IQR 71-83] years) were included. Comorbidities such as hypertension (69.2%), dyslipidaemia (48.6%), cardiovascular diseases (any chronic heart disease in 38.4% and cerebrovascular disease in 12.5%), and chronic lung disease (25.3%) were prevalent, and 49.6% were on ACEI/ARBs. Patients aged 75 years and older suffered more in-hospital complications (respiratory failure, heart failure, renal failure, sepsis) and a significantly higher mortality (18.4 vs. 48.2%, P < 0.001), but fewer admissions to intensive care units (11.2 vs. 4.8%). In the overall cohort, multivariable analysis demonstrated age ≥75 (OR 3.54), chronic kidney disease (OR 3.36), dementia (OR 8.06), peripheral oxygen saturation at admission <92% (OR 5.85), severe lymphopenia (<500/mm3) (OR 3.36) and qSOFA (Quick Sequential Organ Failure Assessment Score) >1 (OR 8.31) to be independent predictors of mortality.patients aged ≥65 years hospitalised for COVID-19 had high rates of in-hospital complications and mortality, especially among patients 75 years or older. Age ≥75 years, dementia, peripheral oxygen saturation <92%, severe lymphopenia and qSOFA scale >1 were independent predictors of mortality in this population. |
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| DOI: | doi:10.1093/ageing/afaa258 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1093/ageing/afaa258 |
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| | DOI: https://doi.org/10.1093/ageing/afaa258 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| K10plus-PPN: | 1770079327 |
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| Verknüpfungen: | → Zeitschrift |
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Clinical profile and predictors of in-hospital mortality among older patients hospitalised for COVID-19 / Becerra-Muñoz, Víctor Manuel [VerfasserIn]; 2021 (Online-Ressource)
