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Verfasst von:Homagk, Ann-Kathrin Verena [VerfasserIn]   i
 Umathum, Reiner [VerfasserIn]   i
 Bock, Michael [VerfasserIn]   i
 Hallscheidt, Peter [VerfasserIn]   i
Titel:Initial in vivo experience with a novel type of MR-Safe Pushable Coils for MR-Guided Embolizations
Verf.angabe:Ann-Kathrin Homagk, Reiner Umathum, Michael Bock, and Peter Hallscheidt
Jahr:2013
Umfang:7 S.
Fussnoten:Gesehen am 21.09.2021
Titel Quelle:Enthalten in: Investigative radiology
Ort Quelle:Philadelphia, Pa. : Lippincott Williams & Wilkins, 1966
Jahr Quelle:2013
Band/Heft Quelle:48(2013), 6, Seite 485-491
ISSN Quelle:1536-0210
Abstract:Objective - Conventional detachable embolization coils are made from platinum or stainless steel and may thus be a magnetic resonance (MR) safety hazard because of resonant device heating. The objective of this experimental study was to assess the feasibility of MR-guided embolization procedures with a novel type of nonmetallic and, therefore, intrinsically MR-safe pushable coil. - Materials and Methods - The embolization coils are made from a polymer and coated with a hydrogel, which expands during contact with liquids. Magnetic resonance-guided embolizations were performed in 6 healthy domestic pigs by deploying up to 3 polymer pushable coils via an active tracking catheter under real-time magnetic resonance imaging monitoring. To assess the renal perfusion deficit induced by the coil embolization, intra-arterial 3-dimensional contrast-enhanced magnetic resonance angiography (3D ce-MRA) data sets were acquired before and every 5 minutes after coil placement until complete vessel occlusion. - Results - The MR-guided embolizations were successful in 5 of the 6 animals. The 3D ce-MRA data sets indicated first perfusion deficits within 2 to 40 minutes after coil deployment. Complete vessel occlusion was achieved after 6 to 53 minutes. In 1 animal, no perfusion defect could be detected. Because our experiments were designed as a preliminary proof-of-concept study, different sizes and numbers of all-polymer hydrocoils were deployed at different anatomical positions, making the drawing of correlation between the size/number of deployed coils and the occlusion efficiency difficult. The all-polymer hydrocoils did not induce any artifacts on the MR images, either in the real-time MR images, which were recorded during the embolization, or in the subsequently acquired 3D ce-MRA images. - Conclusions - Our results demonstrated that the novel all-polymer and intrinsically MR-safe pushable hydrocoils may become a promising tool for MR-guided embolization procedures.
DOI:doi:10.1097/RLI.0b013e3182856a6f
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1097/RLI.0b013e3182856a6f
 Volltext: https://journals.lww.com/investigativeradiology/Fulltext/2013/06000/Initial_In_Vivo_Experience_With_a_Novel_Type_of.18.a ...
 DOI: https://doi.org/10.1097/RLI.0b013e3182856a6f
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1771307943
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