Status: Bibliographieeintrag
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| Online-Ressource |
Verfasst von: | Homagk, Ann-Kathrin Verena [VerfasserIn]  |
| Umathum, Reiner [VerfasserIn]  |
| Bock, Michael [VerfasserIn]  |
| Hallscheidt, Peter [VerfasserIn]  |
Titel: | Initial in vivo experience with a novel type of MR-Safe Pushable Coils for MR-Guided Embolizations |
Verf.angabe: | Ann-Kathrin Homagk, Reiner Umathum, Michael Bock, and Peter Hallscheidt |
Jahr: | 2013 |
Umfang: | 7 S. |
Fussnoten: | Gesehen am 21.09.2021 |
Titel Quelle: | Enthalten in: Investigative radiology |
Ort Quelle: | Philadelphia, Pa. : Lippincott Williams & Wilkins, 1966 |
Jahr Quelle: | 2013 |
Band/Heft Quelle: | 48(2013), 6, Seite 485-491 |
ISSN Quelle: | 1536-0210 |
Abstract: | Objective - Conventional detachable embolization coils are made from platinum or stainless steel and may thus be a magnetic resonance (MR) safety hazard because of resonant device heating. The objective of this experimental study was to assess the feasibility of MR-guided embolization procedures with a novel type of nonmetallic and, therefore, intrinsically MR-safe pushable coil. - Materials and Methods - The embolization coils are made from a polymer and coated with a hydrogel, which expands during contact with liquids. Magnetic resonance-guided embolizations were performed in 6 healthy domestic pigs by deploying up to 3 polymer pushable coils via an active tracking catheter under real-time magnetic resonance imaging monitoring. To assess the renal perfusion deficit induced by the coil embolization, intra-arterial 3-dimensional contrast-enhanced magnetic resonance angiography (3D ce-MRA) data sets were acquired before and every 5 minutes after coil placement until complete vessel occlusion. - Results - The MR-guided embolizations were successful in 5 of the 6 animals. The 3D ce-MRA data sets indicated first perfusion deficits within 2 to 40 minutes after coil deployment. Complete vessel occlusion was achieved after 6 to 53 minutes. In 1 animal, no perfusion defect could be detected. Because our experiments were designed as a preliminary proof-of-concept study, different sizes and numbers of all-polymer hydrocoils were deployed at different anatomical positions, making the drawing of correlation between the size/number of deployed coils and the occlusion efficiency difficult. The all-polymer hydrocoils did not induce any artifacts on the MR images, either in the real-time MR images, which were recorded during the embolization, or in the subsequently acquired 3D ce-MRA images. - Conclusions - Our results demonstrated that the novel all-polymer and intrinsically MR-safe pushable hydrocoils may become a promising tool for MR-guided embolization procedures. |
DOI: | doi:10.1097/RLI.0b013e3182856a6f |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1097/RLI.0b013e3182856a6f |
| Volltext: https://journals.lww.com/investigativeradiology/Fulltext/2013/06000/Initial_In_Vivo_Experience_With_a_Novel_Type_of.18.a ... |
| DOI: https://doi.org/10.1097/RLI.0b013e3182856a6f |
Datenträger: | Online-Ressource |
Sprache: | eng |
K10plus-PPN: | 1771307943 |
Verknüpfungen: | → Zeitschrift |
Initial in vivo experience with a novel type of MR-Safe Pushable Coils for MR-Guided Embolizations / Homagk, Ann-Kathrin Verena [VerfasserIn]; 2013 (Online-Ressource)
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