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| Verfasst von: | Schmitt, Stefan [VerfasserIn]  |
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| | Mailänder, Volker [VerfasserIn] |
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| | Egerer, Gerlinde [VerfasserIn] |
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| | Leo, Albrecht [VerfasserIn] |
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| | Becker, Sven [VerfasserIn] |
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| | Reinhardt, P. [VerfasserIn] |
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| | Wiesneth, M. [VerfasserIn] |
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| | Schrezenmeier, H. [VerfasserIn] |
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| | Ho, Anthony Dick [VerfasserIn] |
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| | Goldschmidt, Hartmut [VerfasserIn] |
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| | Möhler, Thomas [VerfasserIn] |
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| Titel: | Successful autologous peripheral blood stem cell transplantation in a Jehovah’s Witness with multiple myeloma |
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| Titelzusatz: | review of literature and recommendations for high-dose chemotherapy without support of allogeneic blood products |
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| Verf.angabe: | S. Schmitt, V. Mailaender, G. Egerer, A. Leo, S. Becker, P. Reinhardt, M. Wiesneth, H. Schrezenmeier, A.D. Ho, H. Goldschmidt, T.M. Moehler |
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| E-Jahr: | 2008 |
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| Jahr: | 4 March 2008 |
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| Umfang: | 9 S. |
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| Illustrationen: | Diagramme |
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| Fussnoten: | Gesehen am 13.10.2021 |
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| Titel Quelle: | Enthalten in: International journal of hematology |
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| Ort Quelle: | Tokyo [u.a.] : Springer, 1995 |
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| Jahr Quelle: | 2008 |
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| Band/Heft Quelle: | 87(2008), 3 vom: März, Seite 289-297 |
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| ISSN Quelle: | 1865-3774 |
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| Abstract: | We present a case report of a successful high-dose melphalan therapy and autologous stem cell transplantation without the use of allogeneic blood product support in a 70-year-old patient suffering from multiple myeloma. Based on the experience in this case and thorough evaluation of the literature, we consider pre-transplant Hb level of 11-12 g/dl, platelet count higher than 70/nl, good WHO performance status of two and lower and informed consent as important eligibility criteria. During cytopenia recommended supportive measures include growth factor support with erythropoietin and G-CSF, p.o. iron treatment as well as prophylactic use of anti-fibrinloytic agents. Furthermore we discuss additional options that might be considered depending on the individual factors as e.g. pre-transplant collection and cryoconservation of autologous platelet concentrates. Moreover, an analysis of socio-economic issues regarding this procedure is presented. We conclude that allogeneic blood product free transplantation is a feasible procedure that can be offered to the patients belonging to distinct religious groups refusing allogeneic blood products as Jehova´s Witnesses and patients presenting other contraindications for transfusions. |
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| DOI: | doi:10.1007/s12185-008-0055-x |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1007/s12185-008-0055-x |
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| | DOI: https://doi.org/10.1007/s12185-008-0055-x |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| K10plus-PPN: | 177356028X |
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| Verknüpfungen: | → Zeitschrift |
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Successful autologous peripheral blood stem cell transplantation in a Jehovah’s Witness with multiple myeloma / Schmitt, Stefan [VerfasserIn]; 4 March 2008 (Online-Ressource)
