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Verfasst von:Bender, Stephan [VerfasserIn]   i
 Weisbrod, Matthias [VerfasserIn]   i
 Just, Ulrike [VerfasserIn]   i
 Pfüller, Ute [VerfasserIn]   i
 Parzer, Peter [VerfasserIn]   i
 Resch, Franz [VerfasserIn]   i
 Oelkers-Ax, Rieke [VerfasserIn]   i
Titel:Lack of age-dependent development of the contingent negative variation (CNV) in migraine children?
Verf.angabe:S Bender, M Weisbrod, U Just, U Pfüller, P Parzer, F Resch, R Oelkers-Ax
E-Jahr:2002
Jahr:23 April 2002
Umfang:5 S.
Teil:volume:22
 year:2002
 number:2
 pages:132-136
 extent:5
Fussnoten:Gesehen am 14.10.2021
Titel Quelle:Enthalten in: Cephalalgia
Ort Quelle:London [u.a.] : Sage, 1981
Jahr Quelle:2002
Band/Heft Quelle:22(2002), 2, Seite 132-136
ISSN Quelle:1468-2982
Abstract:Increased negativity of contingent negative variation (CNV) in adult migraineurs is thought to reflect cortical hyperexcitability. CNV amplitude changes with age in healthy adults. Recently, evidence emerged that this might not be the case for migraineurs. Our study investigates age-dependency of CNV during childhood age. Seventy-six healthy controls and 61 children with migraine without aura (IHS code 1.1) between 6 and 18 years were examined using an acoustic S1-S2-CNV-paradigm with a 3-s inter-stimulus interval. The amplitude of the late component of CNV, as well as total CNV at the vertex (Cz according to the international 10-20 system), were significantly higher in migraineurs without aura than in controls. Healthy controls showed increasing amplitudes of CNV with age, whereas in migraine children without aura amplitudes did not change. Thus group differences were reduced during adolescence. Increased CNV negativity might reflect a biological vulnerability to migraine, rather than being a result of chronification. Migraineurs seem to lack age-dependent development of CNV also during early age, which supports the hypothesis of migraine as a maturation disorder.
DOI:doi:10.1046/j.1468-2982.2002.00334.x
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Volltext: https://doi.org/10.1046/j.1468-2982.2002.00334.x
 Verlag: https://onlinelibrary.wiley.com/doi/abs/10.1046/j.1468-2982.2002.00334.x
 DOI: https://doi.org/10.1046/j.1468-2982.2002.00334.x
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:Age factors
 childhood
 contingent negative variation
 migraine
K10plus-PPN:1773856812
Verknüpfungen:→ Zeitschrift

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