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Verfasst von:Vassos, Nikolaos [VerfasserIn]   i
 Perrakis, Aristotelis [VerfasserIn]   i
 Schmid, Axel [VerfasserIn]   i
 Croner, Roland [VerfasserIn]   i
 Grützmann, Robert [VerfasserIn]   i
 Agaimy, Abbas [VerfasserIn]   i
Titel:Diffuse neuromatosis of intrahepatic and extrahepatic bile ducts as a rare cause of jaundice
Verf.angabe:Nikolaos Vassos, Aristotelis Perrakis, Axel Schmid, Roland S. Croner, Robert Gruetzmann, Abbas Agaimy
E-Jahr:2021
Jahr:June 2021
Umfang:7 S.
Fussnoten:Gesehen am 19.10.2021 ; Published online: September 30, 2020
Titel Quelle:Enthalten in: Visceral medicine
Ort Quelle:Basel : Karger, 2016
Jahr Quelle:2021
Band/Heft Quelle:37(2021), 3, Seite 226-232
ISSN Quelle:2297-475X
Abstract:Background: Neuroma of the biliary tree is extremely rare with no more than 100 cases reported so far. They mostly present with obstructive jaundice and have been commonly described after surgery or abdominal trauma. Although involvement of the extrahepatic bile duct is far more common, occurrence in the intrahepatic ducts has not so far been reported. Case Report: We describe 3 cases of diffuse biliary tree neuroma affecting 3 females aged 53-68 years. None had a history of neurofibromatosis type1. All presented with progressive obstructive jaundice with no evidence of gallstones. A history of previous surgery was noted in 2 patients. Initial impression on clinical and imaging examination was highly suspicious for bile duct carcinoma in 2 patients. Histology showed diffuse neuromatous proliferation replacing and thickening the bile duct walls. The third patient had concurrent neuroma and recurrent cholangiocarcinoma causing great clinical confusion as initial biopsy showed only benign neuroma, but CA 19-9 was steadily increasing, necessitating a second biopsy which then confirmed recurrent carcinoma. <b><i>Conclusion: This uncommon cause of long-distance bile duct stenosis and progressive jaundice should be included in the differential diagnosis of bile duct neoplasms, in particular when there is a previous surgical history in this abdominal region.
DOI:doi:10.1159/000510486
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1159/000510486
 Volltext: https://www.karger.com/Article/FullText/510486
 DOI: https://doi.org/10.1159/000510486
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1774456109
Verknüpfungen:→ Zeitschrift

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