Partially reversible cardiomyopathy after renal transplant associated with anti-troponin I antibodies

• Verfasst von: Nunes, José Pedro L. [VerfasserIn]
• Verfasst von: Faria, Maria do Sameiro [VerfasserIn]
• Verfasst von: Sampaio, Susana [VerfasserIn]
• Verfasst von: Quintas, José [VerfasserIn]
• Verfasst von: Katus, Hugo [VerfasserIn]
• Verfasst von: Kaya, Ziya [VerfasserIn]
• Titel: Partially reversible cardiomyopathy after renal transplant associated with anti-troponin I antibodies
• Verf.angabe: José Pedro L. Nunes, Maria do Sameiro Faria, Susana Sampaio, José Quintas, Hugo A. Katus, Ziya Kaya
• E-Jahr: 2013
• Jahr: August 31, 2013
• Umfang: 2 S.
• Fussnoten: Gesehen am 29.11.2021
• Titel Quelle: Enthalten in: Cardiology
• Ort Quelle: Basel : Karger, 1970
• Jahr Quelle: 2013
• Band/Heft Quelle: 126(2013), 3, Seite 173-174
• ISSN Quelle: 1421-9751
• DOI: doi:10.1159/000353262
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1779735510

Abstract

Cardiomyopathy associated with dialysis has been shown to be reversible in some cases. A 58-year-old female patient with polycystic renal disease and end-stage renal disease had a renal transplant after 9 years on hemodialysis. Dilated cardiomyopathy with depressed left ventricular ejection fraction markedly improved after transplantation, with normalization of the ejection fraction. High titers for anti-troponin I antibodies were measured: IgG 1:640, IgM 1:80. In our case, the presence of anticardiac (anti-troponin I) antibodies may suggest that the syndrome of reversible cardiomyopathy seen after renal transplantation is associated with immunosuppression therapy acting on immunological mechanisms previously at play.