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Verfasst von:Neuenfeldt, Friederike S. [VerfasserIn]   i
 Weigand, Markus A. [VerfasserIn]   i
 Fischer, Dania [VerfasserIn]   i
Titel:Coagulopathies in intensive care medicine
Titelzusatz:balancing act between thrombosis and bleeding
Verf.angabe:Friederike S. Neuenfeldt, Markus A. Weigand and Dania Fischer
E-Jahr:2021
Jahr:18 November 2021
Umfang:17 S.
Fussnoten:Gesehen am 16.12.2021 ; This article belongs to the special issue "Patient blood management in critical care medicine"
Titel Quelle:Enthalten in: Journal of Clinical Medicine
Ort Quelle:Basel : MDPI, 2012
Jahr Quelle:2021
Band/Heft Quelle:10(2021), 22, special issue, Artikel-ID 5369, Seite 1-17
ISSN Quelle:2077-0383
Abstract:Patient Blood Management advocates an individualized treatment approach, tailored to each patient’s needs, in order to reduce unnecessary exposure to allogeneic blood products. The optimization of hemostasis and minimization of blood loss is of high importance when it comes to critical care patients, as coagulopathies are a common phenomenon among them and may significantly impact morbidity and mortality. Treating coagulopathies is complex as thrombotic and hemorrhagic conditions may coexist and the medications at hand to modulate hemostasis can be powerful. The cornerstones of coagulation management are an appropriate patient evaluation, including the individual risk of bleeding weighed against the risk of thrombosis, a proper diagnostic work-up of the coagulopathy’s etiology, treatment with targeted therapies, and transfusion of blood product components when clinically indicated in a goal-directed manner. In this article, we will outline various reasons for coagulopathy in critical care patients to highlight the aspects that need special consideration. The treatment options outlined in this article include anticoagulation, anticoagulant reversal, clotting factor concentrates, antifibrinolytic agents, desmopressin, fresh frozen plasma, and platelets. This article outlines concepts with the aim of the minimization of complications associated with coagulopathies in critically ill patients. Hereditary coagulopathies will be omitted in this review.
DOI:doi:10.3390/jcm10225369
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext ; Verlag: https://doi.org/10.3390/jcm10225369
 Volltext: https://www.mdpi.com/2077-0383/10/22/5369
 DOI: https://doi.org/10.3390/jcm10225369
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:bleeding
 coagulation
 coagulopathy
 critical care
K10plus-PPN:1782375848
Verknüpfungen:→ Zeitschrift

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