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| Verfasst von: | Abdallah Khalafallah, Alhossain [VerfasserIn]  |
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| | Egerer, Gerlinde [VerfasserIn] |
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| | Goldschmidt, Hartmut [VerfasserIn] |
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| | Wannenmacher, Michael [VerfasserIn] |
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| | Körbling, Martin [VerfasserIn] |
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| | Ho, Anthony Dick [VerfasserIn] |
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| Titel: | Continuous complete remission in adult patients with acute lymphocytic leukaemia at a median observation of 12 years after autologous bone marrow transplantation |
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| Verf.angabe: | Alhossain Abdallah, Gerlinde Egerer, Hartmut Goldschmidt, Michael Wannenmacher, Martin Körbling, Anthony D. Ho |
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| E-Jahr: | 2001 |
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| Jahr: | 20 December 2001 |
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| Umfang: | 4 S. |
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| Fussnoten: | Gesehen am 21.12.2021 |
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| Titel Quelle: | Enthalten in: British journal of haematology |
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| Ort Quelle: | Oxford [u.a.] : Wiley-Blackwell, 1955 |
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| Jahr Quelle: | 2001 |
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| Band/Heft Quelle: | 112(2001), 4, Seite 1012-1015 |
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| ISSN Quelle: | 1365-2141 |
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| Abstract: | We report our long-term experience with autologous bone marrow transplantation (ABMT) for 32 adult patients with acute lymphocytic leukaemia (ALL) in second or later remission (CR), or in first CR but with high-risk. Bone marrow was purged with mafosfamide (n = 25) or with immunomagnetic beads and monoclonal antibodies (n = 7). Retrospective analysis showed that 12 out of 32 patients were in continuous complete remission (CCR) at a median of 143 months (range 66-181 months). A plateau was reached at 50 months and the disease-free and overall survival rates were both 37·5%. It was notable that durable CCR could be achieved for patients in second (three out of nine) or third (one out of six) CR. ABMT could produce durable CCR and the long-term outcome compared favourably with those reported for allogeneic transplantation. |
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| DOI: | doi:10.1046/j.1365-2141.2001.02634.x |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: https://doi.org/10.1046/j.1365-2141.2001.02634.x |
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| | Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1046/j.1365-2141.2001.02634.x |
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| | DOI: https://doi.org/10.1046/j.1365-2141.2001.02634.x |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | acute lymphocytic leukaemia |
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| | autologous bone marrow transplantation |
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| | continuous complete remission |
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| | long-term outcome |
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| | purging |
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| K10plus-PPN: | 1782652787 |
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| Verknüpfungen: | → Zeitschrift |
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Continuous complete remission in adult patients with acute lymphocytic leukaemia at a median observation of 12 years after autologous bone marrow transplantation / Abdallah Khalafallah, Alhossain [VerfasserIn]; 20 December 2001 (Online-Ressource)
