| |  Online-Ressource |
|---|
| Verfasst von: | Abumayyaleh, Mohammad S. A. [VerfasserIn]  |
|---|
| | Nuñez-Gil, Iván J. [VerfasserIn] |
|---|
| | El-Battrawy, Ibrahim [VerfasserIn] |
|---|
| | Estrada, Vicente [VerfasserIn] |
|---|
| | Becerra-Muñoz, Víctor Manuel [VerfasserIn] |
|---|
| | Uribarri, Aitor [VerfasserIn] |
|---|
| | Fernández-Rozas, Inmaculada [VerfasserIn] |
|---|
| | Feltes, Gisela [VerfasserIn] |
|---|
| | Arroyo-Espliguero, Ramón [VerfasserIn] |
|---|
| | Trabattoni, Daniela [VerfasserIn] |
|---|
| | López Pais, Javier [VerfasserIn] |
|---|
| | Pepe, Martino [VerfasserIn] |
|---|
| | Romero, Rodolfo [VerfasserIn] |
|---|
| | Ortega-Armas, María Elizabeth [VerfasserIn] |
|---|
| | Bianco, Matteo [VerfasserIn] |
|---|
| | Astrua, Thamar Capel [VerfasserIn] |
|---|
| | D'Ascenzo, Fabrizio [VerfasserIn] |
|---|
| | Fabregat-Andres, Oscar [VerfasserIn] |
|---|
| | Ballester, Andrea [VerfasserIn] |
|---|
| | Marín, Francisco [VerfasserIn] |
|---|
| | Buonsenso, Danilo [VerfasserIn] |
|---|
| | Sanchez-Gimenez, Raul [VerfasserIn] |
|---|
| | Weiß, Christel [VerfasserIn] |
|---|
| | Fernandez Perez, Cristina [VerfasserIn] |
|---|
| | Fernández-Ortiz, Antonio [VerfasserIn] |
|---|
| | Macaya, Carlos [VerfasserIn] |
|---|
| | Akın, Ibrahim [VerfasserIn] |
|---|
| Titel: | Sepsis of patients infected by SARS-CoV-2 |
|---|
| Titelzusatz: | real-world experience from the international HOPE-COVID-19-Registry and Validation of HOPE Sepsis Score |
|---|
| Verf.angabe: | Mohammad Abumayyaleh, Iván J. Nuñez-Gil, Ibrahim El-Battrawy, Vicente Estrada, Víctor Manuel Becerra-Muñoz, Aitor Uribarri, Inmaculada Fernández-Rozas, Gisela Feltes, Ramón Arroyo-Espliguero, Daniela Trabattoni, Javier López Pais, Martino Pepe, Rodolfo Romero, María Elizabeth Ortega-Armas, Matteo Bianco, Thamar Capel Astrua, Fabrizio D'Ascenzo, Oscar Fabregat-Andres, Andrea Ballester, Francisco Marín, Danilo Buonsenso, Raul Sanchez-Gimenez, Christel Weiß, Cristina Fernandez Perez, Antonio Fernández-Ortiz, Carlos Macaya, Ibrahim Akin and HOPE COVID-19 investigators |
|---|
| E-Jahr: | 2021 |
|---|
| Jahr: | 14 October 2021 |
|---|
| Umfang: | 10 S. |
|---|
| Fussnoten: | Gesehen am 23.12.2021 |
|---|
| Titel Quelle: | Enthalten in: Frontiers in medicine |
|---|
| Ort Quelle: | Lausanne : Frontiers Media, 2014 |
|---|
| Jahr Quelle: | 2021 |
|---|
| Band/Heft Quelle: | 8(2021) vom: 14. Okt., Artikel-ID 728102, Seite 1-10 |
|---|
| ISSN Quelle: | 2296-858X |
|---|
| Abstract: | Background: Patients with sepsis with a concomitant coronavirus (COVID-19) infection are related to a high morbidity and mortality rate. We investigated a large cohort of patients with sepsis with a concomitant COVID-19, and we developed a risk score for the estimation of sepsis risk in COVID-19.Methods: We conducted a sub-analysis from the international Health Outcome Predictive Evaluation Registry for COVID-19 (HOPE-COVID-19-Registry, NCT04334291). Out of 5,837 patients with COVID-19, 624 patients were diagnosed with sepsis according to the Sepsis-3 International Consensus.Results: In multivariable analysis, the following risk factors were identified as independent predictors for developing sepsis: current smoking, tachypnoea (>22 breath per minute), hemoptysis, peripheral oxygen saturation (SpO2) <92%, blood pressure (BP) (systolic BP <90 mmHg and diastolic BP <60 mmHg), Glasgow Coma Scale (GCS) <15, elevated procalcitonin (PCT), elevated troponin I (TnI), and elevated creatinine >1.5 mg/dl. By assigning odds ratio (OR) weighted points to these variables, the following three risk categories were defined to develop sepsis during admission: low-risk group (probability of sepsis 3.1-11.8%); intermediate-risk group (24.8-53.8%); and high-risk-group (58.3-100%). A score of 1 was assigned to current smoking, tachypnoea, decreased SpO2, decreased BP, decreased GCS, elevated PCT, TnI, and creatinine, whereas a score of 2 was assigned to hemoptysis.Conclusions: The HOPE Sepsis Score including nine parameters is useful in identifying high-risk COVID-19 patients to develop sepsis. Sepsis in COVID-19 is associated with a high mortality rate. |
|---|
| DOI: | doi:10.3389/fmed.2021.728102 |
|---|
| URL: | kostenfrei: Volltext: https://doi.org/10.3389/fmed.2021.728102 |
|---|
| | kostenfrei: Volltext: https://www.frontiersin.org/article/10.3389/fmed.2021.728102 |
|---|
| | DOI: https://doi.org/10.3389/fmed.2021.728102 |
|---|
| Datenträger: | Online-Ressource |
|---|
| Sprache: | eng |
|---|
| K10plus-PPN: | 1783545968 |
|---|
| Verknüpfungen: | → Zeitschrift |
|---|
| |
|
|---|
| | |
|---|
| Lokale URL UB: |  Zum Volltext |
|---|
Sepsis of patients infected by SARS-CoV-2 / Abumayyaleh, Mohammad S. A. [VerfasserIn]; 14 October 2021 (Online-Ressource)
