Clinical profile and short-term outcomes of RT-PCR- positive patients with COVID-19

• Verfasst von: Hasan, Md Zabir [VerfasserIn]
• Verfasst von: Biswas, Nirmol Kumar [VerfasserIn]
• Verfasst von: Aziz, Ahmad Monjurul [VerfasserIn]
• Verfasst von: Chowdhury, Juli [VerfasserIn]
• Verfasst von: Haider, Shams Shabab [VerfasserIn]
• Verfasst von: Sarker, Malabika [VerfasserIn]
• Titel: Clinical profile and short-term outcomes of RT-PCR- positive patients with COVID-19
• Titelzusatz: a cross-sectional study in a tertiary care hospital in Dhaka, Bangladesh
• Verf.angabe: Md Zabir Hasan, Nirmol Kumar Biswas, Ahmad Monjurul Aziz, Juli Chowdhury, Shams Shabab Haider, Malabika Sarker
• E-Jahr: 2021
• Jahr: December 15, 2021
• Umfang: 13 S.
• Fussnoten: Gesehen am 27.01.2022
• Titel Quelle: Enthalten in: BMJ open
• Ort Quelle: London : BMJ Publishing Group, 2011
• Jahr Quelle: 2021
• Band/Heft Quelle: 11(2021), 12, Artikel-ID e055126, Seite 1-13
• ISSN Quelle: 2044-6055
• DOI: doi:10.1136/bmjopen-2021-055126
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: COVID-19
• Sach-SW: epidemiology
• Sach-SW: infectious diseases
• Sach-SW: pathology
• Sach-SW: public health
• Sach-SW: therapeutics
• K10plus-PPN: 1787337634

Abstract

Objective The COVID-19 pandemic is still raging worldwide. While there is significant published evidence on the attributes of patients with COVID-19 from lower-income and middle-income countries, there is a dearth of original research published from Bangladesh, a low-income country in Southeast Asia. Based on a case series from a tertiary healthcare centre, this observational study has explored the epidemiology, clinical profile of patients with COVID-19 and short-term outcomes in Dhaka, Bangladesh. - Design and setting A total of 422 COVID-19-confirmed patients (via reverse transcription-PCR test) were enrolled in this study (male=271, female=150, 1 unreported). We have compiled medical records of the patients and descriptively reported their demographic, socioeconomic and clinical features, treatment history, health outcomes, and postdischarge complications. - Result Patients were predominantly male (64%), between 35 and 49 years (28%), with at least one comorbidity (52%), and had COVID-19 symptoms for 1 week before hospitalisation (66%). A significantly higher proportion (p<0.05) of male patients had diabetes, hypertension and ischaemic heart disease, while female patients had asthma (p<0.05). The most common symptoms were fever (80%), cough (60%), dyspnoea (41%) and sore throat (21%). The majority of the patients received antibiotics (77%) and anticoagulant therapy (56%) and stayed in the hospital for an average of 12 days. Over 90% of patients were successfully weaned, while 3% died from COVID-19, and 41% reported complications after discharge. - Conclusion The diversity of clinical and epidemiological characteristics and health outcomes of patients with COVID-19 across age groups and gender is noteworthy. Our result will inform the clinicians and epidemiologists of Bangladesh of their COVID-19 mitigation effort.