| Online-Ressource |
Verfasst von: | Sánchez-Porras, Renán [VerfasserIn]  |
| Zheng, Zelong [VerfasserIn]  |
| Santos, Edgar [VerfasserIn]  |
| Schöll, Michael [VerfasserIn]  |
| Unterberg, Andreas [VerfasserIn]  |
| Sakowitz, Oliver [VerfasserIn]  |
Titel: | The role of spreading depolarization in subarachnoid hemorrhage |
Verf.angabe: | R. Sánchez-Porras, Z. Zheng, E. Santos, M. Schöll, A.W. Unterberg and O.W. Sakowitz |
E-Jahr: | 2013 |
Jahr: | 29 March 2013 |
Umfang: | 7 S. |
Fussnoten: | Gesehen am 28.01.2022 |
Titel Quelle: | Enthalten in: European journal of neurology |
Ort Quelle: | Oxford [u.a.] : Wiley-Blackwell, 1994 |
Jahr Quelle: | 2013 |
Band/Heft Quelle: | 20(2013), 8 vom: Aug., Seite 1121-1127 |
ISSN Quelle: | 1468-1331 |
Abstract: | Subarachnoid hemorrhage (SAH) is a devastating disease associated with death and poor functional outcome. Despite decades of intense research and improvements in clinical management, delayed cerebral ischaemia (DCI) remains the most important cause of morbidity and mortality after SAH. The key role of angiographic cerebral vasospasm, thought to be the main cause of DCI, has been questioned. Emerging evidence suggests that DCI is likely to have a multifactorial etiology. Over the last few years, spreading depolarization (SD) has been identified as a potential pathophysiological mechanism contributing to DCI. The presence of cortical spreading ischaemia, due to an inverse hemodynamic response to SD, offers a possible explanation for DCI and requires more intensive research. Understanding the role of SD as another mechanism inducing DCI and its relationship with other pathological factors could instigate the development of new approaches to the diagnosis and treatment of DCI in order to improve the clinical outcome. |
DOI: | doi:10.1111/ene.12139 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: https://doi.org/10.1111/ene.12139 |
| Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1111/ene.12139 |
| DOI: https://doi.org/10.1111/ene.12139 |
Datenträger: | Online-Ressource |
Sprache: | eng |
Sach-SW: | delayed cerebral ischaemia |
| spreading depolarization |
| spreading ischaemia |
| subarachnoid hemorrhage |
K10plus-PPN: | 178736500X |
Verknüpfungen: | → Zeitschrift |
¬The¬ role of spreading depolarization in subarachnoid hemorrhage / Sánchez-Porras, Renán [VerfasserIn]; 29 March 2013 (Online-Ressource)