High hydrostatic pressure effects investigated by neutron scattering on lipid multilamellar vesicles

• Verfasst von: Trapp, Marcus [VerfasserIn]
• Verfasst von: Marion, Jérémie [VerfasserIn]
• Verfasst von: Tehei, Moeava [VerfasserIn]
• Verfasst von: Demé, Bruno [VerfasserIn]
• Verfasst von: Gutberlet, Thomas [VerfasserIn]
• Verfasst von: Peters, Judith [VerfasserIn]
• Titel: High hydrostatic pressure effects investigated by neutron scattering on lipid multilamellar vesicles
• Verf.angabe: Marcus Trapp, Jérémie Marion, Moeava Tehei, Bruno Demé, Thomas Gutberlet and Judith Peters
• E-Jahr: 2013
• Jahr: 28 Oct 2013
• Umfang: 6 S.
• Fussnoten: Gesehen am 10.02.2022
• Titel Quelle: Enthalten in: Physical chemistry, chemical physics
• Ort Quelle: Cambridge : RSC Publ., 1999
• Jahr Quelle: 2013
• Band/Heft Quelle: 15(2013), 48, Seite 20951-20956
• ISSN Quelle: 1463-9084
• DOI: doi:10.1039/C3CP52762J
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1789208203

Abstract

The effects of high hydrostatic pressure on the structure and dynamics of model membrane systems were investigated using neutron scattering. Diffraction experiments show shifts of the pre- and main-phase transitions of multilamellar vesicles of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) to higher temperatures with increased pressure which are close to results observed previously by other techniques, namely (10.4 ± 1.0) K kbar−1 and (20.0 ± 0.5) K kbar−1 for the two transitions. Backscattering spectroscopy reveals that the mean square displacements in the liquid phase are about 10% smaller at 300 bar and about 20% smaller at 600 bar compared to atmospheric pressure, whereas in the gel phase below the main phase transition the mean square displacements show a smaller difference in the dynamics of the three pressure values within the studied pressure range.