| |  Online-Ressource |
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| Verfasst von: | Han, Jessie [VerfasserIn]  |
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| | Harrison, Luke [VerfasserIn] |
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| | Patzelt, Lisa [VerfasserIn] |
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| | Wu, Mingming [VerfasserIn] |
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| | Junker, Daniela [VerfasserIn] |
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| | Herzig, Stephan [VerfasserIn] |
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| | Berriel Diaz, Mauricio [VerfasserIn] |
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| | Karampinos, Dimitrios C. [VerfasserIn] |
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| Titel: | Imaging modalities for diagnosis and monitoring of cancer cachexia |
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| Verf.angabe: | Jessie Han, Luke Harrison, Lisa Patzelt, Mingming Wu, Daniela Junker, Stephan Herzig, Mauricio Berriel Diaz and Dimitrios C. Karampinos |
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| E-Jahr: | 2021 |
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| Jahr: | 23 September 2021 |
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| Umfang: | 18 S. |
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| Fussnoten: | Gesehen am 18.02.2022 |
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| Titel Quelle: | Enthalten in: EJNMMI Research |
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| Ort Quelle: | Berlin : Springer, 2011 |
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| Jahr Quelle: | 2021 |
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| Band/Heft Quelle: | 11(2021), Artikel-ID 94, Seite 1-18 |
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| ISSN Quelle: | 2191-219X |
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| Abstract: | Cachexia, a multifactorial wasting syndrome, is highly prevalent among advanced-stage cancer patients. Unlike weight loss in healthy humans, the progressive loss of body weight in cancer cachexia primarily implicates lean body mass, caused by an aberrant metabolism and systemic inflammation. This may lead to disease aggravation, poorer quality of life, and increased mortality. Timely detection is, therefore, crucial, as is the careful monitoring of cancer progression, in an effort to improve management, facilitate individual treatment and minimize disease complications. A detailed analysis of body composition and tissue changes using imaging modalities—that is, computed tomography, magnetic resonance imaging, (18F) fluoro-2-deoxy-d-glucose (18FDG) PET and dual-energy X-ray absorptiometry—shows great premise for charting the course of cachexia. Quantitative and qualitative changes to adipose tissue, organs, and muscle compartments, particularly of the trunk and extremities, could present important biomarkers for phenotyping cachexia and determining its onset in patients. In this review, we present and compare the imaging techniques that have been used in the setting of cancer cachexia. Their individual limitations, drawbacks in the face of clinical routine care, and relevance in oncology are also discussed. |
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| DOI: | doi:10.1186/s13550-021-00834-2 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
kostenfrei: Volltext: https://doi.org/10.1186/s13550-021-00834-2 |
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| | DOI: https://doi.org/10.1186/s13550-021-00834-2 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Adipose tissue |
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| | Cancer cachexia progression |
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| | Computed tomography (CT) |
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| | Imaging biomarkers |
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| | Imaging-based phenotyping |
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| | Magnetic resonance imaging (MRI) |
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| | Skeletal muscle |
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| K10plus-PPN: | 1790158656 |
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| Verknüpfungen: | → Zeitschrift |
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Imaging modalities for diagnosis and monitoring of cancer cachexia / Han, Jessie [VerfasserIn]; 23 September 2021 (Online-Ressource)
