Bilateral vertebral artery dissection, agenesis of both ICAs, and connective tissue aberrations

• Verfasst von: Lill, Christina Maria [VerfasserIn]
• Verfasst von: Günther-Kunkel, Kristin [VerfasserIn]
• Verfasst von: Hoch, Heinrich [VerfasserIn]
• Verfasst von: Paul, Friedemann [VerfasserIn]
• Verfasst von: Grond-Ginsbach, Caspar [VerfasserIn]
• Verfasst von: Haußer-Siller, Ingrid [VerfasserIn]
• Verfasst von: Zipp, Frauke [VerfasserIn]
• Titel: Bilateral vertebral artery dissection, agenesis of both ICAs, and connective tissue aberrations
• Verf.angabe: Christina M. Lill, MD, Kristin Günther-Kunkel, MD, Heinrich Hoch, MD, Friedemann Paul, MD, Caspar Grond-Ginsbach, PhD, Ingrid Hausser, PhD, Frauke Zipp, MD
• E-Jahr: 2013
• Jahr: April 8, 2013
• Umfang: 2 S.
• Fussnoten: Gesehen am 03.03.2022
• Titel Quelle: Enthalten in: Neurology
• Ort Quelle: Philadelphia, Pa. : Wolters Kluwer, 1951
• Jahr Quelle: 2013
• Band/Heft Quelle: 80(2013), 15 vom: Apr., Seite 1442-1443
• ISSN Quelle: 1526-632X
• DOI: doi:10.1212/WNL.0b013e31828c2f8e
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1794606157

Abstract

A 35-year-old woman presented with acute signs of stroke (appendix e-1 on the Neurology® Web site at [www.neurology.org][1]). After initial CT with angiography, MRI with time-of-flight angiography confirmed agenesis of both internal carotid arteries (ICAs; figure 1A). It revealed bilateral vertebral artery (VA) dissections and ischemias in both middle artery territories (figure 1, A-E). Skin biopsy microscopy (figure 2) was consistent with ultrastructural connective tissue disease (uCTD), for which no further evidence was found apart from mild hypermobility of the finger joints. The underlying uCTD with structural instability of the arterial walls and the increased blood flow in the vertebrobasilar circulation due to the bilateral ICA agenesis may have promoted VA dissection. - - [1]: http://www.neurology.org/