| |  Online-Ressource |
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| Verfasst von: | Tagkalos, Evangelos [VerfasserIn]  |
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| | van der Sluis, P. C. [VerfasserIn] |
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| | Berlth, Felix [VerfasserIn] |
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| | Poplawski, A. [VerfasserIn] |
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| | Hadzijusufovic, E. [VerfasserIn] |
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| | Lang, H. [VerfasserIn] |
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| | van Berge Henegouwen, M. I. [VerfasserIn] |
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| | Gisbertz, S. S. [VerfasserIn] |
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| | Müller, Beat P. [VerfasserIn] |
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| | Ruurda, J. P. [VerfasserIn] |
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| | Schiesser, M. [VerfasserIn] |
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| | Schneider, P. M. [VerfasserIn] |
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| | van Hillegersberg, R. [VerfasserIn] |
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| | Grimminger, P. P. [VerfasserIn] |
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| Titel: | Robot-assisted minimally invasive thoraco-laparoscopic esophagectomy versus minimally invasive esophagectomy for resectable esophageal adenocarcinoma, a randomized controlled trial (ROBOT-2 trial) |
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| Verf.angabe: | E. Tagkalos, P.C. van der Sluis, F. Berlth, A. Poplawski, E. Hadzijusufovic, H. Lang, M.I. van Berge Henegouwen, S.S. Gisbertz, B.P. Müller-Stich, J.P. Ruurda, M. Schiesser, P.M. Schneider, R. van Hillegersberg and P.P. Grimminger |
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| E-Jahr: | 2021 |
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| Jahr: | 26 September 2021 |
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| Umfang: | 12 S. |
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| Fussnoten: | Published online: 26 September 2021 ; Gesehen am 09.03.2022 |
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| Titel Quelle: | Enthalten in: BMC cancer |
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| Ort Quelle: | London : BioMed Central, 2001 |
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| Jahr Quelle: | 2021 |
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| Band/Heft Quelle: | 21(2021), Artikel-ID 1060, Seite 1-12 |
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| ISSN Quelle: | 1471-2407 |
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| Abstract: | Background: For patients with esophageal adenocarcinoma or cancer of the gastroesophageal junction, radical esophagectomy with 2-field lymphadenectomy is the cornerstone of the multimodality treatment with curative intent. Both conventional minimally invasive esophagectomy (MIE) and robot assisted minimally invasive esophagectomy (RAMIE) were shown to be superior compared to open transthoracic esophagectomy considering postoperative complications. However, no randomized comparison exists between MIE and RAMIE in the Western World for patients with esophageal adenocarcinoma. Methods: This is an investigator-initiated and investigator-driven multicenter randomized controlled parallel-group superiority trial. All adult patients (age ≥ 18 and ≤ 90 years) with histologically proven, surgically resectable (cT1-4a, N0-3, M0) esophageal adenocarcinoma of the intrathoracic esophagus or adenocarcinoma of the gastroesophageal junction and with European Clinical Oncology Group performance status 0, 1 or 2 will be assessed for eligibility and included after obtaining informed consent. Patients (n = 218) with resectable esophageal adenocarcinoma of the intrathoracic esophagus or adenocarcinoma of the gastroesophageal junction are randomized to either RAMIE (n = 109) or MIE (n = 109). The primary outcome of this study is the total number of resected abdominal and mediastinal lymph nodes specified per lymph node station. |
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| DOI: | doi:10.1186/s12885-021-08780-x |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: https://doi.org/10.1186/s12885-021-08780-x |
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| | Volltext: https://bmccancer.biomedcentral.com/articles/10.1186/s12885-021-08780-x |
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| | DOI: https://doi.org/10.1186/s12885-021-08780-x |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| K10plus-PPN: | 1795130768 |
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| Verknüpfungen: | → Zeitschrift |
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Robot-assisted minimally invasive thoraco-laparoscopic esophagectomy versus minimally invasive esophagectomy for resectable esophageal adenocarcinoma, a randomized controlled trial (ROBOT-2 trial) / Tagkalos, Evangelos [VerfasserIn]; 26 September 2021 (Online-Ressource)
