| Online-Ressource |
Verfasst von: | Hernando-Harder, Ana C. [VerfasserIn]  |
| Franke, Andreas [VerfasserIn]  |
| Wedel, Thilo [VerfasserIn]  |
| Böttner, Martina [VerfasserIn]  |
| Krammer, H. [VerfasserIn]  |
| Singer, Manfred V. [VerfasserIn]  |
| Harder, Hermann [VerfasserIn]  |
Titel: | Intestinal gas retention in patients with idiopathic slow-transit constipation |
Verf.angabe: | Ana Cristina Hernando-Harder, Andreas Franke, Thilo Wedel, Martina Böttner, Heinz-Juergen Krammer, Manfred Vincenz Singer, Hermann Harder |
E-Jahr: | 2007 |
Jahr: | 24 March 2007 |
Umfang: | 9 S. |
Fussnoten: | Gesehen am 16.03.2022 |
Titel Quelle: | Enthalten in: Digestive diseases and sciences |
Ort Quelle: | Dordrecht : Springer Science + Business Media B.V., 1934 |
Jahr Quelle: | 2007 |
Band/Heft Quelle: | 52(2007), 10, Seite 2667-2675 |
ISSN Quelle: | 1573-2568 |
Abstract: | Patients with slow-transit constipation (STC) have delayed colonic transit for solid und liquid bowel contents but intestinal gas handling has not been studied so far. Different nutrients influence motor and sensory gut function. We hypothesized that, in patients with STC, alteration of regulatory mechanisms may result in impaired intestinal gas dynamics. On 3 separate days, validated gas challenge was performed in 10 STC patients and 10 volunteers during duodenal saline, lipids, or intravenous glucose. During saline only 60% ± 8% of gas was cleared by STC patients after 60-min gas infusion, vs. 91% ± 2% by controls (P < 0.001). Acute hyperglycemia or lipids did not change intestinal gas dynamics in these patients (saline infusion), but compared to healthy subjects, significant intestinal gas retention occurred. In STC, disturbances of intestinal gas dynamics include basal intestinal gas retention, and this is virtually not affected by acute hyperglycemia or duodenal lipids. |
DOI: | doi:10.1007/s10620-006-9671-6 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1007/s10620-006-9671-6 |
| DOI: https://doi.org/10.1007/s10620-006-9671-6 |
Datenträger: | Online-Ressource |
Sprache: | eng |
K10plus-PPN: | 1795744537 |
Verknüpfungen: | → Zeitschrift |
Intestinal gas retention in patients with idiopathic slow-transit constipation / Hernando-Harder, Ana C. [VerfasserIn]; 24 March 2007 (Online-Ressource)