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| Verfasst von: | Sadick, Haneen [VerfasserIn]  |
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| | Bergler, Wolfgang F. [VerfasserIn] |
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| | Oulmi-Kagermann, Jasmina [VerfasserIn] |
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| | Naim, Ramin [VerfasserIn] |
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| | Sadick, Maliha [VerfasserIn] |
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| | Hörmann, Karl [VerfasserIn] |
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| | Riedel, Frank [VerfasserIn] |
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| Titel: | Estriol induced squamous metaplasia on the nasal mucosa in patients with hereditary hemorrhagic telangiectasia |
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| Verf.angabe: | Haneen Sadick, Wolfgang F. Bergler, Jasmina Oulmi-Kagermann, Ramin Naim, Maliha Sadick, Karl Hörmann, Frank Riedel |
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| E-Jahr: | 2005 |
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| Jahr: | [September-October 2005] |
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| Umfang: | 6 S. |
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| Illustrationen: | Illustrationen |
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| Fussnoten: | Gesehen am 25.03.2022 |
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| Titel Quelle: | Enthalten in: Archives of medical research |
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| Ort Quelle: | Amsterdam [u.a.] : Elsevier Science, 1996 |
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| Jahr Quelle: | 2005 |
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| Band/Heft Quelle: | 36(2005), 5 vom: Sept./Okt., Seite 468-473 |
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| ISSN Quelle: | 1873-5487 |
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| Abstract: | Background - The aim of this study was to evaluate by light and electron microscopy the effect of topical estriol on the nasal mucosa in patients with hereditary hemorrhagic telangiectasia (HHT). - Methods - Twelve patients were instructed to apply twice daily 0.1% estriol as a nose ointment over a period of 12 months. Written consent was obtained from each patient, allowing biopsy specimens of the nasal mucosa to be taken prior to and 3, 6 and 12 months after estriol application. - Results - Metaplastic change of the nasal mucosa was observed 6 months after topical estriol application. The former ciliated columnar epithelium changed into a keratinizing squamous epithelium. The effect was reversible after discontinuation of estriol application. - Conclusions - For the first time, we could outline the effect of topical estriol on the nasal mucosa. These histomorphological findings, and the fact that estriol is a low-potency metabolite of estradiol, make estriol a valuable agent in the treatment of HHT patients. |
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| DOI: | doi:10.1016/j.arcmed.2005.03.037 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1016/j.arcmed.2005.03.037 |
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| | Volltext: https://www.sciencedirect.com/science/article/pii/S0188440905001360 |
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| | DOI: https://doi.org/10.1016/j.arcmed.2005.03.037 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Estriol |
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| | Hereditary hemorrhagic telangiectasia (HHT) |
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| | Light and electron microscopic study |
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| | Squamous metaplasia |
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| | Topical estrogens |
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| K10plus-PPN: | 1796701289 |
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| Verknüpfungen: | → Zeitschrift |
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Estriol induced squamous metaplasia on the nasal mucosa in patients with hereditary hemorrhagic telangiectasia / Sadick, Haneen [VerfasserIn]; [September-October 2005] (Online-Ressource)
