| Online-Ressource |
Verfasst von: | Karck, Matthias [VerfasserIn]  |
| Kallenbach, Klaus [VerfasserIn]  |
| Hagl, Christian Matthias [VerfasserIn]  |
| Aichele, Christine [VerfasserIn]  |
| Leyh, Rainer Günther [VerfasserIn]  |
| Haverich, Axel [VerfasserIn]  |
Titel: | Aortic root surgery in Marfan syndrome |
Titelzusatz: | comparison of aortic valve-sparing reimplantation versus composite grafting |
Verf.angabe: | Matthias Karck, MD, Klaus Kallenbach, MD, Christian Hagl, MD, Christine Rhein, MD, Rainer Leyh, MD, Axel Haverich, MD |
E-Jahr: | 2004 |
Jahr: | February 2004 |
Umfang: | 8 S. |
Fussnoten: | Read at the Eighty-third Annual Meeting of The American Association for Thoracic Surgery, Boston, Mass, May 4-7, 2003 ; Gesehen am 30.03.2022 |
Titel Quelle: | Enthalten in: The journal of thoracic and cardiovascular surgery |
Ort Quelle: | Stanford, Calif. : HighWire Press, 1959 |
Jahr Quelle: | 2004 |
Band/Heft Quelle: | 127(2004), 2, Seite 391-398 |
ISSN Quelle: | 1097-685X |
Abstract: | Objective - The objective of this study was to compare the results of aortic valve-sparing reimplantation and aortic root replacement with mechanical valve conduits in patients with Marfan syndrome undergoing operation for aortic root aneurysms. - Patients and methods - Between March 1979 and April 2002, 119 patients with clinical evidence of Marfan syndrome underwent composite graft replacement with mechanical valve conduits (n = 74) or aortic valve-sparing reimplantation according to David (n = 45). The underlying causes were aortic dissection type A (43 patients) and aneurysms (76 patients). - Results - Patients undergoing aortic valve reimplantation were younger compared with patients undergoing composite grafting (28 vs 35 years, P = .002) and had longer intraoperative aortic crossclamp times (125 vs 78 minutes, P < .0001) and extracorporeal circulation times (162 vs 124 minutes, P < .0001). Early postoperative mortality was 6.8% (n = 5) in patients undergoing composite grafting and 0% in patients undergoing aortic valve reimplantation (P = .15). Mean follow-up was 30 months for patients undergoing aortic valve reimplantation and 114 months for patients undergoing composite grafting. Freedom from reoperation and death after 5 years postoperatively was 92% and 89% in patients undergoing composite grafting and 84% and 96% in patients undergoing aortic valve reimplantation (P = .31; P = .54), respectively. Thromboembolic complications or late postoperative bleeding occurred in 17 patients undergoing composite grafting, and an early postoperative event occurred in 1 patient undergoing aortic valve reimplantation. - Conclusions - The results of aortic valve reimplantation and composite grafting of the aortic valve and ascending aorta with mechanical valve conduits are similar with regard to early and mid-term postoperative mortality and to the incidence of late reoperations in patients with Marfan syndrome. The low risk of thromboembolic or bleeding complications favors aortic valve reimplantation in these patients. |
DOI: | doi:10.1016/j.jtcvs.2003.07.049 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: https://doi.org/10.1016/j.jtcvs.2003.07.049 |
| Volltext: https://www.sciencedirect.com/science/article/pii/S0022522303016064 |
| DOI: https://doi.org/10.1016/j.jtcvs.2003.07.049 |
Datenträger: | Online-Ressource |
Sprache: | eng |
Sach-SW: | 26 |
| 35 |
K10plus-PPN: | 1797029762 |
Verknüpfungen: | → Zeitschrift |
Aortic root surgery in Marfan syndrome / Karck, Matthias [VerfasserIn]; February 2004 (Online-Ressource)