| |  Online-Ressource |
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| Verfasst von: | Rehnitz, Julia [VerfasserIn]  |
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| | Messmer, Birgitta [VerfasserIn] |
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| | Bender, Ulrike [VerfasserIn] |
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| | Nguyen, Xuan Phuoc [VerfasserIn] |
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| | Germeyer, Ariane [VerfasserIn] |
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| | Hinderhofer, Katrin [VerfasserIn] |
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| | Strowitzki, Thomas [VerfasserIn] |
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| | Capp, Edison [VerfasserIn] |
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| Titel: | Activation of AKT/mammalian target of rapamycin signaling in the peripheral blood of women with premature ovarian insufficiency and its correlation with FMR1 expression |
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| Verf.angabe: | Julia Rehnitz, Birgitta Messmer, Ulrike Bender, Xuan Phuoc Nguyen, Ariane Germeyer, Katrin Hinderhofer, Thomas Strowitzki and Edison Capp |
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| E-Jahr: | 2022 |
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| Jahr: | 05 March 2022 |
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| Umfang: | 7 S. |
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| Fussnoten: | Gesehen am 05.04.2022 |
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| Titel Quelle: | Enthalten in: Reproductive biology and endocrinology |
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| Ort Quelle: | London : Biomed Central, 2003 |
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| Jahr Quelle: | 2022 |
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| Band/Heft Quelle: | 20(2022), Artikel-ID 44, Seite 1-7 |
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| ISSN Quelle: | 1477-7827 |
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| Abstract: | The protein kinase B (AKT)/mammalian target of rapamycin (mTOR) signaling pathway regulates early follicular activation and follicular pool maintenance in female germline cells. Fragile X mental retardation 1 (FMR1) regulates folliculogenesis and it is variably expressed in patients with Premature Ovary Insufficiency. FMR1 expression is supposed to be linked to AKT/mTOR signaling in an ovarian response dependent manner as demonstrated in recent in vitro and in vivo studies in the female germline in vitro and in vivo. |
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| DOI: | doi:10.1186/s12958-022-00919-0 |
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| URL: | kostenfrei: Volltext: https://doi.org/10.1186/s12958-022-00919-0 |
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| | DOI: https://doi.org/10.1186/s12958-022-00919-0 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | AKT |
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| | Fragile X mental retardation 1 gene |
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| | Mammalian target of rapamycin |
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| | Premature ovarian insufficiency |
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| | S6 kinase |
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| | Tuberous sclerosis complex 2 |
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| K10plus-PPN: | 1797664107 |
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| Verknüpfungen: | → Zeitschrift |
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| Lokale URL UB: |  Zum Volltext |
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Activation of AKT/mammalian target of rapamycin signaling in the peripheral blood of women with premature ovarian insufficiency and its correlation with FMR1 expression / Rehnitz, Julia [VerfasserIn]; 05 March 2022 (Online-Ressource)
