Status: Bibliographieeintrag
Standort: ---
Exemplare:
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| Online-Ressource |
Verfasst von: | Thomas, Martin Alexander [VerfasserIn]  |
| Fleissner, Gerta [VerfasserIn]  |
| Hauptfleisch, Stefan [VerfasserIn]  |
| Lemmer, Björn [VerfasserIn]  |
Titel: | Subcellular identification of angiotensin I/II- and angiotensin II (AT1)-receptor-immunoreactivity in the central nervous system of rats |
Verf.angabe: | Martin Alexander Thomas, Gerta Fleissner, Stefan Hauptfleisch, Björn Lemmer |
Jahr: | 2003 |
Umfang: | 13 S. |
Fussnoten: | Available online 17 December 2002 ; Im Titel ist die Ziffer 1 tiefgestellt ; Gesehen am 07.04.2022 |
Titel Quelle: | Enthalten in: Brain research |
Ort Quelle: | Amsterdam : Elsevier, 1966 |
Jahr Quelle: | 2003 |
Band/Heft Quelle: | 962(2003), 1/2, Seite 92-104 |
ISSN Quelle: | 1872-6240 |
Abstract: | To gain insight into generating and transport mechanisms of angiotensin (ANG) in the brain the study was focused on the subcellular localization of ANG II and its AT1-receptors in the hypothalamus of rats. The present paper demonstrates ANG II- and AT1-receptor-immunolabelling at brain parenchyma vessels and at glial and neuronal structures in the perivascular region. Further, ANG II- and AT1-receptor-immunoreactivity is shown at plasma membranes and intracellular structures in the ependyma of the third ventricle. Based upon a conventional horseradish peroxidase technique, combined with the classical substrate 3,3′-diaminobenzidine, a procedure is introduced that will be useful with a variety of antibodies used on glutar- and paraformaldehyde-fixed brain tissue. This technique enables a fast correlation between light and electron microscopical results and might also provide an attractive alternative to colloidal gold-labelling and silver-intensification techniques. |
DOI: | doi:10.1016/S0006-8993(02)03971-9 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1016/S0006-8993(02)03971-9 |
| Volltext: https://www.sciencedirect.com/science/article/pii/S0006899302039719 |
| DOI: https://doi.org/10.1016/S0006-8993(02)03971-9 |
Datenträger: | Online-Ressource |
Sprache: | eng |
Sach-SW: | Angiotensin II |
| Angiotensin II (AT)-receptor |
| Brain parenchyma vessel |
| Electron microscopy |
| Hypothalamus |
| Immunocytochemistry |
K10plus-PPN: | 1798056925 |
Verknüpfungen: | → Zeitschrift |
Subcellular identification of angiotensin I/II- and angiotensin II (AT1)-receptor-immunoreactivity in the central nervous system of rats / Thomas, Martin Alexander [VerfasserIn]; 2003 (Online-Ressource)
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