Incidental findings in whole-body MR imaging of a population-based cohort study

• Verfasst von: Schlett, Christopher L. [VerfasserIn]
• Verfasst von: Rospleszcz, Susanne [VerfasserIn]
• Verfasst von: Korbmacher, Dorina [VerfasserIn]
• Verfasst von: Lorbeer, Roberto [VerfasserIn]
• Verfasst von: Auweter, Sigrid [VerfasserIn]
• Verfasst von: Hetterich, Holger [VerfasserIn]
• Verfasst von: Selder, Sonja [VerfasserIn]
• Verfasst von: Heier, Margit [VerfasserIn]
• Verfasst von: Linkohr, Birgit [VerfasserIn]
• Verfasst von: Weckbach, Sabine [VerfasserIn]
• Verfasst von: Ertl-Wagner, Birgit [VerfasserIn]
• Verfasst von: Peters, Annette [VerfasserIn]
• Verfasst von: Bamberg, Fabian [VerfasserIn]
• Titel: Incidental findings in whole-body MR imaging of a population-based cohort study
• Titelzusatz: Frequency, management and psychosocial consequences
• Verf.angabe: Christopher L. Schlett, Susanne Rospleszcz, Dorina Korbmacher, Roberto Lorbeer, Sigrid Auweter, Holger Hetterich, Sonja Selder, Margit Heier, Birgit Linkohr, Sabine Weckbach, Birgit Ertl-Wagner, Annette Peters, Fabian Bamberg
• Jahr: 2021
• Umfang: 6 S.
• Fussnoten: Online Publikationsdatum: 28 November 2020 ; Gesehen am 23.04.2022
• Titel Quelle: Enthalten in: European journal of radiology
• Ort Quelle: Amsterdam [u.a.] : Elsevier Science, 1990
• Jahr Quelle: 2021
• Band/Heft Quelle: 134(2021), Artikel-ID 109451, Seite 1-6
• ISSN Quelle: 1872-7727
• DOI: doi:10.1016/j.ejrad.2020.109451
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Epidemiologic study
• Sach-SW: Incidental finding
• Sach-SW: Patient care management
• Sach-SW: Psychosocial aspects
• Sach-SW: Whole body imaging
• K10plus-PPN: 1800076606

Abstract

Objectives - Management of incidental findings (IF) remains controversial but highly relevant. Our aim was to assess the frequency, management and psychosocial consequences of IF reporting in a population-based cohort study undergoing whole-body MR imaging. - Methods - The study was nested in a prospective cohort from a longitudinal, population-based cohort (KORA-FF4) in southern Germany. All MR obtained on 3T MR scanner were reviewed by board-certified radiologists regarding clinically relevant IF. A baseline and follow-up questionnaires including PHQ-9 were completed prior to and 6-month after to the scan. - Results - Of 400 participants (56.3±9.2years, 58 % male) undergoing whole-body MR, IF were found in 22 % of participants (n=89); most frequently located in the abdominal sequences. In the pre-scan survey, most participants stated as the motivation that they wanted to “contribute to a scientific purpose” (91 %), while “knowing whether I’m healthy” was the most frequent motivation reported 6 months post-scan (88 %). The desire for IF reporting increased over time (pre- vs. 6-months-post-scan), also for clinically less important IF (72 % vs. 84 %, p=0.001). Regarding psychosocial impact, a small portion (3.4 %) reported that awaiting the IF report added “definitely” or “very probably” additional stress burden. Of participants with reported IF, 56.8 % classified the results as “very helpful”. In the post-scan survey moderate depression was observed in 3.3 % and severe depression in 1.2 %. This did not differ between participants with and without reported IF. - Conclusion - In a cohort with whole-body MR imaging, the prevalence of IF was high. Participants considered reporting of IF highly important and added only minor psychological burden.