Status: Bibliographieeintrag
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| Verfasst von: | Siegmund, Sören Volker [VerfasserIn]  |
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| | Haas, Stephan [VerfasserIn] |
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| | Schneider, Alexander [VerfasserIn] |
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| | Singer, Manfred V. [VerfasserIn] |
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| Titel: | Animal models in gastrointestinal alcohol research |
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| Titelzusatz: | a short appraisal of the different models and their results |
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| Verf.angabe: | Sören Siegmund, Stephan Haas, Alexander Schneider, Manfred V. Singer |
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| E-Jahr: | 2003 |
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| Jahr: | 20 June 2003 |
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| Umfang: | 24 S. |
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| Fussnoten: | Gesehen am 25.04.2022 |
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| Titel Quelle: | Enthalten in: Best practice & research. Clinical gastroenterology |
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| Ort Quelle: | London [u.a.] : Harcourt, 1999 |
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| Jahr Quelle: | 2003 |
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| Band/Heft Quelle: | 17(2003), 4 vom: Aug., Seite 519-542 |
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| ISSN Quelle: | 1532-1916 |
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| Abstract: | Alcohol-related diseases of the gastrointestinal tract play an important role in clinical gastroenterology. However, the mechanisms and pathophysiology underlying the effects of ethanol on the organs of the digestive tract are not yet completely understood. Animal models represent an essential tool for investigating alcohol-related diseases because they give researchers the opportunity to use methods that cannot be used in humans, such as knockout technology. However, there is still a need for new animal models resembling the human condition, since for some alcohol-related diseases such as chronic alcoholic pancreatitis, the ideal animal model does not yet exist. In this chapter, we provide an overview of the most commonly used animal models in gastrointestinal alcohol research. We will also briefly discuss the current concepts of the pathophysiological mechanisms involved in acute and chronic alcoholic damage of the oesophagus, stomach, small and large intestine, pancreas and liver. |
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| DOI: | doi:10.1016/S1521-6918(03)00033-7 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1016/S1521-6918(03)00033-7 |
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| | Volltext: https://www.sciencedirect.com/science/article/pii/S1521691803000337 |
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| | DOI: https://doi.org/10.1016/S1521-6918(03)00033-7 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | alcohol |
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| | alcohol-related diseases |
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| | alcoholic beverages |
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| | alcoholic liver disease |
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| | alcoholic pancreatitis |
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| | animal models |
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| | ethanol |
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| | gastrointestinal organs |
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| | humans |
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| | large intestine |
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| | liver |
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| | oesophagus |
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| | pancreas |
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| | review |
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| | small intestine |
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| | stomach |
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| K10plus-PPN: | 1800100930 |
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| Verknüpfungen: | → Zeitschrift |
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Animal models in gastrointestinal alcohol research / Siegmund, Sören Volker [VerfasserIn]; 20 June 2003 (Online-Ressource)
68910436
