Status: Bibliographieeintrag
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| Verfasst von: | Hoffmann, Ursula [VerfasserIn]  |
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| | Huhle, Günter [VerfasserIn] |
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| | Rossol-Haseroth, Karin [VerfasserIn] |
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| | Heene, Dieter L. [VerfasserIn] |
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| | Harenberg, Job [VerfasserIn] |
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| Titel: | A fatal complication in a patient with heparin-induced thrombocytopenia type II re-exposed to heparin |
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| Verf.angabe: | U. Hoffmann, G. Huhle, K. Haseroth, D.L. Heene, J. Harenberg |
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| E-Jahr: | 1999 |
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| Jahr: | 01 September 1999 |
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| Umfang: | 3 S. |
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| Fussnoten: | Gesehen am 05.05.2022 |
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| Titel Quelle: | Enthalten in: European journal of orthopaedic surgery & traumatology |
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| Ort Quelle: | Paris : Springer France, 1991 |
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| Jahr Quelle: | 1999 |
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| Band/Heft Quelle: | 9(1999), 3, Seite 205-207 |
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| ISSN Quelle: | 1432-1068 |
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| Abstract: | The heparin-induced thrombocytopenia type II is a rare but important drug related complication associated with thrombocytopenia and thrombosis. We report on a patient with elective revision of the total hip arthroplasty. Preoperatively for nineteen days, the patient received unfractionated heparin 5000 IU three times daily for thromboprophylaxis. Postoperatively the patient developed a platelet drop from 236000/μl to 69000/μl an iliac vein thrombosis and pulmonary embolism. In assumption of heparin induced thrombocytopenia anticoagulation was switched to danaparoid-sodium subcutaneously. Platelet count rised to normal values while three days. Because of a negative heparin-induced platelet aggregation assay, anticoagulation was switched to a PTT controlled high dose intravenous unfractionated heparin. Two days after re-exposition to heparin platelet counts dropped to 34000/μl blood. The patient died 12 days after readministration of heparin due to respiratory and circulatory failure. Postmortem analysis of serum revealed positive heparin/platelet factor 4 IgG-antibodies. |
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| DOI: | doi:10.1007/BF00542596 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1007/BF00542596 |
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| | DOI: https://doi.org/10.1007/BF00542596 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Arthroplastie de hanche |
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| | Heparin |
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| | Hip-replacement |
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| | Reexposition |
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| | Réexposition |
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| | Thrombocytopenia |
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| | Thrombocytopénie |
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| K10plus-PPN: | 1801016186 |
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| Verknüpfungen: | → Zeitschrift |
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¬A¬ fatal complication in a patient with heparin-induced thrombocytopenia type II re-exposed to heparin / Hoffmann, Ursula [VerfasserIn]; 01 September 1999 (Online-Ressource)
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