| |  Online-Ressource |
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| Verfasst von: | Roeber, Sigrun [VerfasserIn]  |
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| | Bäzner, Hansjörg [VerfasserIn] |
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| | Hennerici, Michael G. [VerfasserIn] |
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| | Porstmann, Romy [VerfasserIn] |
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| | Kretzschmar, Hans A. [VerfasserIn] |
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| Titel: | Neurodegeneration with features of NIFID and ALS - extended clinical and neuropathological spectrum |
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| Verf.angabe: | Sigrun Roeber, Hansjoerg Bäzner, Michael Hennerici, Romy Porstmann, Hans A. Kretzschmar |
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| E-Jahr: | 2006 |
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| Jahr: | 4 August 2006 |
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| Umfang: | 7 S. |
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| Fussnoten: | Gesehen am 06.05.2022 |
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| Titel Quelle: | Enthalten in: Brain pathology |
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| Ort Quelle: | Oxford : Wiley-Blackwell, 1990 |
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| Jahr Quelle: | 2006 |
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| Band/Heft Quelle: | 16(2006), 3, Seite 228-234 |
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| ISSN Quelle: | 1750-3639 |
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| Abstract: | Heterogeneous clinical and neuropathological features have been observed in the recently described neuronal intermediate filament inclusion disease (NIFID). The immunohistological findings common to all cases are alpha-internexin and neurofilament-positive neuronal cytoplasmic inclusions, which have not been found in comparable density in other neurodegenerative disorders. Notwithstanding these common features, the cases reported so far have shown differences concerning age at onset, constellation and dominance of symptoms as well as type and distribution of additional neuropathological findings. Here we present the first NIFID case that exhibits severe involvement of lower motor neurons. Also, this patient may have had a clinical onset of disease in early childhood, as she was diagnosed as having dysarthria, which could not be attributed to any other cause at the age of 3 years. This case is a further contribution to the spectrum of this novel neurodegenerative disease. |
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| DOI: | doi:10.1111/j.1750-3639.2006.00013.x |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1111/j.1750-3639.2006.00013.x |
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| | DOI: https://doi.org/10.1111/j.1750-3639.2006.00013.x |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Adolescent |
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| | Adult |
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| | Amyotrophic Lateral Sclerosis |
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| | Brain |
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| | Cerebral Palsy |
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| | Child |
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| | Child, Preschool |
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| | Diagnosis, Differential |
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| | Female |
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| | Humans |
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| | Immunohistochemistry |
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| | Inclusion Bodies |
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| | Infant |
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| | Infant, Newborn |
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| | Intermediate Filaments |
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| | Nerve Degeneration |
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| | Neurodegenerative Diseases |
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| | Neurons |
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| | Pantothenate Kinase-Associated Neurodegeneration |
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| | Rett Syndrome |
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| | Spastic Paraplegia, Hereditary |
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| K10plus-PPN: | 180112759X |
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| Verknüpfungen: | → Zeitschrift |
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Neurodegeneration with features of NIFID and ALS - extended clinical and neuropathological spectrum / Roeber, Sigrun [VerfasserIn]; 4 August 2006 (Online-Ressource)
