Topical estrogens combined with argon plasma coagulation in the management of epistaxis in hereditary hemorrhagic telangiectasia

• Verfasst von: Bergler, Wolfgang [VerfasserIn]
• Verfasst von: Sadick, Haneen [VerfasserIn]
• Verfasst von: Riedel, Frank [VerfasserIn]
• Verfasst von: Götte, Karl [VerfasserIn]
• Verfasst von: Hörmann, Karl [VerfasserIn]
• Titel: Topical estrogens combined with argon plasma coagulation in the management of epistaxis in hereditary hemorrhagic telangiectasia
• Verf.angabe: Wolfgang Bergler, Haneen Sadick, Frank Riedel, Karl Götte, Karl Hörmann (Mannheim, Germany)
• E-Jahr: 2002
• Jahr: March 1, 2002
• Umfang: 7 S.
• Illustrationen: Illustrationen
• Fussnoten: Gesehen am 06.05.2022
• Titel Quelle: Enthalten in: Annals of otology, rhinology & laryngology
• Ort Quelle: Thousand Oaks, Calif. : Sage, 1897
• Jahr Quelle: 2002
• Band/Heft Quelle: 111(2002), 3, Seite 222-228
• ISSN Quelle: 1943-572X
• DOI: doi:10.1177/000348940211100306
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: argon plasma coagulation
• Sach-SW: epistaxis
• Sach-SW: hereditary hemorrhagic telangiectasia
• Sach-SW: topical estrogen
• K10plus-PPN: 1801153531

Abstract

The aim of this study was to assess the value of topically applied estrogens in patients with hereditary hemorrhagic telangiectasia. Twenty-six patients with this disorder were treated with argon plasma coagulation and randomized into 2 groups: group A, which had postoperative application of estriol ointment (n = 14), and group B, which had postoperative application of dexpanthenol ointment (n = 12). Over a period of 12 months, the frequency and intensity of bleeding, the patient's satisfaction, and the success of the treatment were evaluated with a questionnaire. Before the operation, more than 90% of the patients in both groups complained of daily episodes of epistaxis. Twelve months after treatment, the frequency and intensity of bleeding had significantly decreased in group A as compared to group B. Of the patients in group A, 93% were satisfied with the treatment. Of the patients in group B, only 42% were satisfied with the treatment. In both groups, more than 90% of the patients were willing to undergo the same treatment again. The combined treatment approach with argon plasma coagulation and topical estriol enables us to significantly prolong the hemorrhage-free interval.