Navigation überspringen
Universitätsbibliothek Heidelberg
Standort: ---
Exemplare: ---
heiBIB
 Online-Ressource
Verfasst von:Schuh, Fabian [VerfasserIn]   i
 Fink, Matthias A. [VerfasserIn]   i
 Feißt, Manuel [VerfasserIn]   i
 Eckert, Christoph [VerfasserIn]   i
 Dörr-Harim, Colette [VerfasserIn]   i
 Knebel, Phillip [VerfasserIn]   i
 Diener, Markus K. [VerfasserIn]   i
 Büchler, Markus W. [VerfasserIn]   i
 Mihaljevic, André Leopold [VerfasserIn]   i
 Probst, Pascal [VerfasserIn]   i
Titel:Protocol of a prospective study investigating the association of PAncreatic parenchymal RISk factors with postoperative pancreatic fistula after partial pancreaticoduodenectomy (PARIS trial)
Verf.angabe:Fabian Schuh, Matthias A. Fink, Manuel Feisst, Christoph Eckert, Colette Dörr-Harim, Phillip Knebel, Markus K. Diener, Markus W. Büchler, André L. Mihaljevic, Pascal Probst
E-Jahr:2022
Jahr:April 13, 2022
Umfang:7 S.
Fussnoten:Gesehen am 11.05.2022
Titel Quelle:Enthalten in: BMJ open
Ort Quelle:London : BMJ Publishing Group, 2011
Jahr Quelle:2022
Band/Heft Quelle:12(2022), 4, Artikel-ID e054138, Seite 1-7
ISSN Quelle:2044-6055
Abstract:Introduction Partial pancreatoduodenectomy (PD) is the treatment of choice for many malignant and benign diseases of the pancreatic head. Postoperative complication rates of up to 40% are regularly reported. One of the most common and potentially life-threatening complication is the postoperative pancreatic fistula (POPF). Parenchymal risk factors like main pancreatic duct diameter or texture of the pancreatic gland have already been identified in retrospective studies. The aim of this study is to evaluate the diagnostic value of parenchymal risk factors on POPF in a prospective manner. - Methods and analysis All patients scheduled for elective PD at the Department of General, Visceral and Transplantation Surgery of the University of Heidelberg will be screened for eligibility. As diagnostic factors, diameter and texture of the pancreatic gland as well as radiological and histopathological features will be recorded. Furthermore, the new four class risk classification system by the International Study Group of Pancreatic Surgery (ISGPS) will be recorded. The postoperative course will be monitored prospectively. The primary endpoint will be the association of the main pancreatic duct size and the texture of the pancreatic gland on POPF according to the updated ISGPS definition. The diagnostic value of the above-mentioned factors for POPF will be evaluated in a univariable and multivariable analysis. - Ethics and dissemination PARIS is a monocentric, prospective, diagnostic study to evaluate the association of parenchymal risk factors and the development of POPF approved by the Ethics Committee of the medical faculty of Heidelberg University (S-344/2019). Results will be available in 2022 and will be published at national and international meetings. With this knowledge, the intraoperative and perioperative decision-making process could be eased and improve the individual outcome of patient. - Trial registration number DRKS00017184.
DOI:doi:10.1136/bmjopen-2021-054138
URL:kostenfrei: Volltext: https://doi.org/10.1136/bmjopen-2021-054138
 kostenfrei: Volltext: https://bmjopen.bmj.com/content/12/4/e054138
 DOI: https://doi.org/10.1136/bmjopen-2021-054138
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:Adult surgery
 Hepatobiliary surgery
 Pancreatic surgery
K10plus-PPN:1801190178
Verknüpfungen:→ Zeitschrift
 
 
Lokale URL UB: Zum Volltext

Permanenter Link auf diesen Titel (bookmarkfähig):  https://katalog.ub.uni-heidelberg.de/titel/68916228   QR-Code
zum Seitenanfang