Matrix metalloproteinases in cerebrovascular diseases

• Verfasst von: Fatar, Marc [VerfasserIn]
• Verfasst von: Stroick, Mark Gregor [VerfasserIn]
• Verfasst von: Griebe, Martin [VerfasserIn]
• Verfasst von: Hennerici, Michael G. [VerfasserIn]
• Titel: Matrix metalloproteinases in cerebrovascular diseases
• Verf.angabe: Marc Fatar, Mark Stroick, Martin Griebe, Michael Hennerici
• E-Jahr: 2005
• Jahr: July 27, 2005
• Umfang: 11 S.
• Fussnoten: Gesehen am 10.05.2022
• Titel Quelle: Enthalten in: Cerebrovascular diseases
• Ort Quelle: Basel : Karger, 1991
• Jahr Quelle: 2005
• Band/Heft Quelle: 20(2005), 3, Seite 141-151
• ISSN Quelle: 1421-9786
• DOI: doi:10.1159/000087197
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Cerebrovascular Disorders
• Sach-SW: Humans
• Sach-SW: Matrix Metalloproteinases
• K10plus-PPN: 1801301352

Abstract

Matrix metalloproteinases are important factors for tissue remodelling and are activated during several physiological and pathological conditions, including cerebrovascular diseases. We give an overview of the structure, production and physiological effects of these widely distributed proteases and describe the genetic background and regulation pathways. In particular, we discuss the role of matrix metalloproteinases in vascular remodelling concerning ischaemic stroke, brain haemorrhage, vascular dementia, carotid artery plaques and cerebral aneurysms.