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Status: Bibliographieeintrag

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Verfasst von:Nikas, Ilias P. [VerfasserIn]   i
 Seide, Svenja [VerfasserIn]   i
 Proctor, Tanja [VerfasserIn]   i
 Kleinaki, Zoi [VerfasserIn]   i
 Kleinaki, Maria [VerfasserIn]   i
 Reynolds, Jordan P. [VerfasserIn]   i
Titel:The Paris System for reporting urinary cytology
Titelzusatz:a meta-analysis
Verf.angabe:Ilias P. Nikas, Svenja Seide, Tanja Proctor, Zoi Kleinaki, Maria Kleinaki and Jordan P. Reynolds
E-Jahr:2022
Jahr:27 January 2022
Umfang:15 S.
Fussnoten:Gesehen am 12.05.2022 ; This article belongs to the special issue "Precision medicine in urologic oncology: diagnosis, treatment and prognosis"
Titel Quelle:Enthalten in: Journal of Personalized Medicine
Ort Quelle:Basel : MDPI, 2011
Jahr Quelle:2022
Band/Heft Quelle:12(2022), 2, special issue, Artikel-ID 170, Seite 1-15
ISSN Quelle:2075-4426
Abstract:The Paris System (TPS) for Reporting Urinary Cytology is a standardized, evidence-based reporting system, comprising seven diagnostic categories: nondiagnostic, negative for high-grade urothelial carcinoma (NHGUC), atypical urothelial cells (AUC), suspicious for high-grade urothelial carcinoma (SHGUC), HGUC, low-grade urothelial neoplasm (LGUN), and other malignancies. This study aimed to calculate the pooled risk of high-grade malignancy (ROHM) of each category and demonstrate the diagnostic accuracy of urine cytology reported with TPS. Four databases (PubMed, Embase, Scopus, Web of Science) were searched. Specific inclusion and exclusion criteria were applied, while data were extracted and analyzed both qualitatively and quantitatively. The pooled ROHM was 17.70% for the nondiagnostic category (95% CI, 0.0650; 0.3997), 13.04% for the NHGUC (95% CI, 0.0932; 0.1796), 38.65% for the AUC (95% CI, 0.3042; 0.4759), 12.45% for the LGUN (95% CI, 0.0431; 0.3101), 76.89 for the SHGUC (95% CI, 0.7063; 0.8216), and 91.79% for the HGUC and other malignancies (95% CI, 0.8722; 0.9482). A summary ROC curve was created and the Area Under the Curve (AUC) was 0.849, while the pooled sensitivity was 0.669 (95% CI, 0.589; 0.741) and false-positive rate was 0.101 (95% CI, 0.063; 0.158). In addition, the pooled DOR of the included studies was 21.258 (95% CI, 14.336; 31.522). TPS assigns each sample into a diagnostic category linked with a specific ROHM, guiding clinical management.
DOI:doi:10.3390/jpm12020170
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.3390/jpm12020170
 Volltext: https://www.mdpi.com/2075-4426/12/2/170
 DOI: https://doi.org/10.3390/jpm12020170
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:bladder cancer
 cytopathology
 diagnostic accuracy
 pathology
 risk of high-grade malignancy (ROHM)
 sensitivity and specificity
 tumor
 urine
 urothelial carcinoma
 urothelial neoplasia
K10plus-PPN:1801693277
Verknüpfungen:→ Zeitschrift

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