| |  Online-Ressource |
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| Verfasst von: | Filler, Jule [VerfasserIn]  |
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| | Krüchten, Ricarda von [VerfasserIn] |
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| | Wawro, Nina [VerfasserIn] |
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| | Maier, Lisa [VerfasserIn] |
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| | Lorbeer, Roberto [VerfasserIn] |
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| | Nattenmüller, Johanna [VerfasserIn] |
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| | Thorand, Barbara [VerfasserIn] |
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| | Bamberg, Fabian [VerfasserIn] |
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| | Peters, Annette [VerfasserIn] |
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| | Schlett, Christopher L. [VerfasserIn] |
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| | Linseisen, Jakob [VerfasserIn] |
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| | Rospleszcz, Susanne [VerfasserIn] |
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| Titel: | Association of habitual dietary intake with liver iron |
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| Titelzusatz: | a population-based imaging study |
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| Verf.angabe: | Jule Filler, Ricarda von Krüchten, Nina Wawro, Lisa Maier, Roberto Lorbeer, Johanna Nattenmüller, Barbara Thorand, Fabian Bamberg, Annette Peters, Christopher L. Schlett, Jakob Linseisen and Susanne Rospleszcz |
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| Jahr: | 2022 |
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| Umfang: | 14 S. |
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| Fussnoten: | Published: 28 December 2021 ; Gesehen am 13.05.2022 |
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| Titel Quelle: | Enthalten in: Nutrients |
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| Ort Quelle: | Basel : MDPI, 2009 |
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| Jahr Quelle: | 2022 |
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| Band/Heft Quelle: | 14(2022), 1, Artikel-ID 132, Seite 1-14 |
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| ISSN Quelle: | 2072-6643 |
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| Abstract: | Iron-related disorders of the liver can result in serious health conditions, such as liver cirrhosis. Evidence on the role of modifiable lifestyle factors like nutrition in liver iron storage is lacking. Thus, we aimed to assess the association of habitual diet with liver iron content (LIC). We investigated 303 participants from the population-based KORA-MRI study who underwent whole-body magnetic resonance imaging (MRI). Dietary habits were evaluated using repeated 24 h food lists and a food frequency questionnaire. Sex-stratified multiple linear regression models were applied to quantify the association between nutrition variables of interest and LIC, adjusting for liver fat content (LFC), energy intake, and age. Mean age of participants was 56.4 ± 9.0 years and 44.2% were female. Mean LIC was 1.23 ± 0.12 mg/g dry weight, with higher values in men than in women (1.26 ± 0.13 and 1.20 ± 0.10 mg/g, p < 0.001). Alcohol intake was positively associated with LIC (men: β = 1.94; women: β = 4.98, p-values < 0.03). Significant negative associations with LIC were found for fiber (β = −5.61, p < 0.001) and potassium (β = −0.058, p = 0.034) for female participants only. Furthermore, LIC was highly correlated with liver fat content in both sexes. Our findings suggests that there are sex-specific associations of habitual dietary intake and LIC. Alcohol, fiber, and potassium may play a considerable role in liver iron metabolism. |
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| DOI: | doi:10.3390/nu14010132 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.3390/nu14010132 |
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| | Volltext: https://www.mdpi.com/2072-6643/14/1/132 |
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| | DOI: https://doi.org/10.3390/nu14010132 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | alcohol |
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| | diet |
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| | iron metabolism |
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| | liver iron |
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| | liver iron overload |
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| | MRI |
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| | nutrition |
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| | population-based |
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| K10plus-PPN: | 1801714576 |
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| Verknüpfungen: | → Zeitschrift |
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Association of habitual dietary intake with liver iron / Filler, Jule [VerfasserIn]; 2022 (Online-Ressource)
