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Verfasst von:Wöhrle, Johannes C. [VerfasserIn]   i
 Behrens, Stephan [VerfasserIn]   i
 Mielke, Orell [VerfasserIn]   i
 Hennerici, Michael G. [VerfasserIn]   i
Titel:Early motor evoked potentials in acute stroke
Titelzusatz:adjunctive measure to MRI for assessment of prognosis in acute stroke within 6 hours
Verf.angabe:Johannes C. Wöhrle, Stephan Behrens, Orell Mielke, Michael G. Hennerici
E-Jahr:2004
Jahr:June 23, 2004
Umfang:5 S.
Fussnoten:Gesehen am 18.05.2022
Titel Quelle:Enthalten in: Cerebrovascular diseases
Ort Quelle:Basel : Karger, 1991
Jahr Quelle:2004
Band/Heft Quelle:18(2004), 2, Seite 130-134
ISSN Quelle:1421-9786
Abstract:BACKGROUND: In acute stroke, a magnetic resonance (MR) perfusion-weighted imaging (PWI) and diffusion-weighted imaging (DWI) mismatch (PWI>DWI mismatch) may indicate tissue at risk for infarction and poor prognosis. However, different to early enthusiasm about this surrogate marker, its validity has shown several drawbacks in individual patients. Rather than relying on imaging, we evaluated motor evoked potentials (MEP) as a measure of cerebral function in the acute stroke setting. - METHODS: Thirteen patients with acute hemiparetic stroke underwent time to peak PWI and DWI within 6 h after onset as well as recordings of early MEP of first dorsal interosseous muscles. Outcome was assessed by the Unified Neurological Stroke Scale and Barthel Index at day 42. - RESULTS: Of 8 patients with PWI>DWI mismatch, 4 patients with normal MEP had a good clinical outcome and 4 patients with absent or pathological MEP had an unfavourable outcome (p < 0.05, Fisher's exact test). In all patients without PWI>DWI mismatch, MEP findings predicted clinical outcome. Normal MEP at day 0--but not PWI/DWI findings--significantly correlated with a good clinical outcome. - CONCLUSIONS: Early MEP recordings in acute stroke patients provide valid prognostic information; they may become more useful for specific treatment decisions than presently available MRI surrogate parameters.
DOI:doi:10.1159/000079265
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1159/000079265
 DOI: https://doi.org/10.1159/000079265
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:Acute Disease
 Aged
 Aged, 80 and over
 Early Diagnosis
 Evoked Potentials, Motor
 Female
 Humans
 Magnetic Resonance Imaging
 Male
 Middle Aged
 Predictive Value of Tests
 Prognosis
 Stroke
K10plus-PPN:1802495096
Verknüpfungen:→ Zeitschrift

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