Biodegradation of absorbable sutures in body fluids and pH buffers

• Verfasst von: Freudenberg, Sebastian [VerfasserIn]
• Verfasst von: Rewerk, Stephan [VerfasserIn]
• Verfasst von: Kaess, Michael [VerfasserIn]
• Verfasst von: Weiß, Christel [VerfasserIn]
• Verfasst von: Dorn-Beinecke, A. [VerfasserIn]
• Verfasst von: Post, Stefan [VerfasserIn]
• Titel: Biodegradation of absorbable sutures in body fluids and pH buffers
• Verf.angabe: S. Freudenberg, S. Rewerk, M. Kaess, Christel Weiss, A. Dorn-Beinecke, S. Post
• Jahr: 2004
• Umfang: 10 S.
• Fussnoten: Gesehen am 31.05.2022
• Titel Quelle: Enthalten in: European surgical research
• Ort Quelle: Basel [u.a.] : Karger, 1969
• Jahr Quelle: 2004
• Band/Heft Quelle: 36(2004), 6, Seite 376-385
• ISSN Quelle: 1421-9921
• DOI: doi:10.1159/000081648
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1805321498

Abstract

Objective: This study measures the influence of body fluids on the loss of tensile strength of absorbable sutures in vitro. Methods: Nine synthetic absorbable sutures were incubated in different gastrointestinal fluids, as well as in blood and three buffers. Stretch tests were performed after days 0, 7, 14, and 21. Results: Tensile strength varied from 18.5 to 32.8 N, and elasticity varied from 9.5 to 51% of the initial length. The influence of pH, blood, and gastric juice was negligible on all sutures except PDS II®. Except for Monocryl®, all sutures, especially Polysorb® and Vicryl®, lost tensile strength much faster in bile, jejunal and pancreatic juices than in the corresponding buffers. Conclusion: The biodegradation of sutures varies greatly in different body fluids independent of differences in pH.