Organ transplantation in the vasculitides

• Verfasst von: Schmitt, Wilhelm [VerfasserIn]
• Verfasst von: Woude, Fokko J. van der [VerfasserIn]
• Titel: Organ transplantation in the vasculitides
• Verf.angabe: Wilhelm H. Schmitt, Fokko J. van der Woude
• Jahr: 2003
• Umfang: 7 S.
• Fussnoten: Gesehen am 03.06.2022
• Titel Quelle: Enthalten in: Current opinion in rheumatology
• Ort Quelle: Philadelphia, Pa. : Lippincott Williams & Wilkins, 1989
• Jahr Quelle: 2003
• Band/Heft Quelle: 15(2003), 1, Seite 22-28
• ISSN Quelle: 1531-6963
• DOI: doi:10.1097/00002281-200301000-00005
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Antibodies, Antineutrophil Cytoplasmic
• Sach-SW: Clinical Trials as Topic
• Sach-SW: Graft Survival
• Sach-SW: Humans
• Sach-SW: Immunosuppressive Agents
• Sach-SW: Kidney Transplantation
• Sach-SW: Postoperative Complications
• Sach-SW: Secondary Prevention
• Sach-SW: Vasculitis
• K10plus-PPN: 1805896199

Abstract

Despite important therapeutic improvements, permanent organ failure may develop in primary systemic vasculitides and affect the heart, the lungs, and especially the kidneys. In systemic vasculitides associated with antineutrophil cytoplasmic antibodies (AASV), end-stage renal failure develops in 20% of cases. Renal transplantation became a beneficial option in these patients, with a graft and patient survival comparable to that in nondiabetic patients. This review summarizes the current knowledge on indications and contraindications for renal transplantation in AASV and discusses the impact of posttransplant immunosuppression on the course of the patients.