Effects of cross-links on motor-mediated filament organization

• Verfasst von: Ziebert, Falko [VerfasserIn]
• Verfasst von: Aranson, Igor S. [VerfasserIn]
• Verfasst von: Tsimring, Lev S. [VerfasserIn]
• Titel: Effects of cross-links on motor-mediated filament organization
• Verf.angabe: Falko Ziebert, Igor S Aranson and Lev S Tsimring
• E-Jahr: 2007
• Jahr: 30 November 2007
• Umfang: 14 S.
• Fussnoten: Gesehen am 21.09.2022
• Titel Quelle: Enthalten in: New journal of physics
• Ort Quelle: [Bad Honnef] : Dt. Physikalische Ges., 1999
• Jahr Quelle: 2007
• Band/Heft Quelle: 9(2007), 11, Artikel-ID 421, Seite 1-14
• ISSN Quelle: 1367-2630
• DOI: doi:10.1088/1367-2630/9/11/421
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1807855864

Abstract

Cross-links and molecular motors play an important role in the organization of cytoskeletal filament networks. Here, we incorporate the effect of cross-links into our model of polar motor-filament organization (Aranson and Tsimring 2005 Phys. Rev. E 71 050901), through suppressing the relative sliding of filaments in the course of motor-mediated alignment. We show that this modification leads to a nontrivial macroscopic behavior, namely the oriented state exhibits a transverse instability in contrast to the isotropic instability that occurs without cross-links. This transverse instability leads to the formation of dense extended bundles of oriented filaments, similar to the recently observed structures in actomyosin. This model can be also applied to situations with two oppositely directed motor species or motors with different processing speeds.